Illumina's portfolio of sequencing systems allow researchers to identify and track methylation patterns by directly sequencing bisulfite-converted DNA, methylation-sensitive restriction digest-enriched fragments, anti-methyl C-precipitated fragments, or chromatin immunoprecipitates of methyltransferases trapped to aza-labeled DNA.

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Correctly map more reads to the methylated genome using accurate 100+ base paired-end reads. Easily prepare highly diverse libraries needed for comprehensive characterization of methylation status. Using Illumina sequencing technology, you can evenly sequence a repetitive bisulfite-converted genome and detect variations in methylation signatures at single-base resolution to pinpoint rare binding events to within 50 bases of the actual binding site.