Since they were first developed in 2005, whole-genome genotyping (WGGT) arrays have become an important tool for discovering variants that contribute to human diseases and phenotypes. The two primary applications of this technology, genome-wide association studies (GWAS) and copy number variant (CNV) analysis, have helped researchers begin to unravel the complex genetic architecture behind diseases such as diabetes and Crohn's disease, and traits such as hair and eye color.

Illumina's WGGT Infinium BeadChips offer researchers the flexibility to genotype samples with hundreds of thousands to millions of markers that deliver dense genome-wide coverage with the most up-to-date content available from the scientific community. Markers on the BeadChips are strategically selected by Illumina scientists to  provide maximum coverage of the genome for both association testing and copy number detection.

Keep up-to-date with recent discoveries by customizing Infinium iSelect HD BeadChips with Infinium Add-On Content. Whether it comes from publically available databases or new discoveries, allows researchers to combine existing marker sets with new, unique content on a single BeadChip, increasing efficiency and cost effectiveness in study design.

HumanCore BeadChip Family

Designed to make large-scale genotyping affordable, these customizable arrays include an informative backbone of tagSNPs, enabling researchers to tailor studies to specific populations or research goals. HumanCore microarrays were developed in collaboration with several leading research institutions. In addition to large genetic studies, they can also be used to quickly and easily obtain baseline sample datasets for sample tracking and QC, as well as perform a variety of downstream applications such as common variant and CNV detection studies.

Learn More about the Core Family of Microarrays

HumanOmni BeadChip Family

This flexible, complimentary family of microarrays represents a revolution in array design, delivering up to 5 million markers per sample and offering an unprecedented amount of customizability. Designed from next-generation sequencing data from international projects such as the 1000 Genomes Project, Omni microarrays deliver unrivaled coverage of the genome. Access to whole-genome sequencing data provides the most complete picture of the extent of variation, allowing Illumina scientists to select the most informative markers to provide superior power to detect trait- and disease-associated variants.

Learn More about the Omni Family of Microarrays

Omni Whole-Genome Arrays
BeadChipArray Format
Markers per Sample
HumanOmni5-Quad 4 ~ 4.3 million
HumanOmni2.5S 8 ~ 2.5 million
HumanOmni2.5-8 8 ~ 2.5 million
HumanOmniExpress 24 ~ 700,000
HumanCytoSNP-12 12 ~ 300,000
Omni Semi-Custom Whole-Genome Arrays
BeadChipArray Format
Markers per Sample
HumanOmni5-Quad+ 4 ~ 4.3 million (fixed)
up to 500K (custom)
HumanOmni2.5S+ 8 ~2.5 million (fixed)
up to 500K (custom)
HumanOmniExpress+
24
~700,000 (fixed)
up to 50K (custom)