Equine SNP50 DNA Analysis Kits

The Equine SNP50 BeadChip was developed through the Illumina iSelect program in collaboration with the International Equine Genome Mapping Workshop and the Morris Animal Foundation's Equine Genome Consortium. The BeadChip features 54,602 highly informative SNPs uniformly distributed across the entire genomes of 15 breeds of horses.

Content is derived from the EquCab2.0 SNP collection compiled by the Broad Institute's Equine Genome Sequencing Project. The researchers discovered more than 940,000 SNPs across Arabian, Andalusian, Akhal-teke, Icelandic, Standardbred, Thoroughbred, and Quarter horse breeds. From this data set, the EquineSNP50 BeadChip developers designed probes that target a subset of uniformly distributed SNPs spanning the entire horse genome.

With an average probe spacing of 43.2kb across all 31 autosomes, the EquineSNP50 BeadChip provides more than sufficient marker information to support whole-genome enabled selection. Over 53,500 probes target polymorphic loci, including 2,254 loci that appear to have an adjacent or third polymorphism such as a deletion or third allele.

This BeadChip enables horse researchers to conduct a broad range of genotyping applications, including genome-wide association studies and Quantitative Trait Loci identification. Designed to enable identification of genes and mutations that contribute to traits of interest in all major horse breeds, this BeadChip offers a powerful platform for improving horse breeding programs. More, it enables the development of new diagnostic and therapeutic approaches to promote equine health and welfare.