OvineSNP50 DNA Analysis Kits

The OvineSNP50 BeadChip was developed in collaboration with leading ovine researchers from AgResearch, Baylor UCSC, CSIRO, and the USDA as part of the International Sheep Genomics Consortium.

The BeadChip features over 54,241 evenly spaced probes that target single nucleotide polymorphisms (SNPs). More than 18,000 of these markers were discovered through sequencing reduced representation libraries with the Illumina Genome Analyzer. A set of 600 SNPs were identified by BAC end sequencing and validated with Illumina GoldenGate Genotyping Assays over 403 animals from 23 breeds. The remaining SNPs were derived from the draft ovine genome.

The OvineSNP50 Genotyping BeadChip provides uniform genome-wide coverage with an estimated one marker per 46kb on average. This BeadChip offers more than sufficient SNP density for genome-wide association studies and other applications such as genome-wide selection, determination of genetic merit, identification of quantitative trait loci, and comparative genetic studies.

The BeadChip is powered by the Infinium HD Assay that provides the industry's highest call rates, allows for flexible content deployment, and enables the detection and measurement of copy number variation.

• The BeadChip further reduces experimental variability by allowing researchers to interrogate up to 12 samples in parallel
• The assay's single-tube sample preparation without PCR or ligation steps significantly reduces labor and potential sample handling errors