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HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase. Harman AN et al. 2009.
HIV-1 can be endocytosed by dendritic cells (DCs) and can then replicate inside them. More...
Harman, Kraus, Bye, Byth, Turville, Tang, Mercier, Nasr, Stern, Slobedman, Driessen, Cunningha HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase. Harman AN et al. 2009.Blood
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Jones S et al. 2009.
The authors used complete sequencing of the protein-coding genes to find familial pancreatic patients with a germline truncating mutation in PALB2, which they posited as a predisposing factor. More...
Jones, Hruban, Kamiyama, Borges, Zhang, Parsons, Lin, Palmisano, Brune, Jaffee, Iacobuzio-Donahue, Maitra, Parmigiani, Kern, Velculescu, Kinzler, Vogelstein, Eshleman, Goggins, Klei Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Jones S et al. 2009.Science
DNA Sudoku--harnessing high-throughput sequencing for multiplexed specimen analysis. Erlich Y et al. 2009.
Multiplexing using next-generation sequencing means DNA from many specimens can be analyzed simultaneously. More...
Erlich, Chang, Gordon, Ronen, Navon, Rooks, Hanno DNA Sudoku--harnessing high-throughput sequencing for multiplexed specimen analysis. Erlich Y et al. 2009.Genome Research
Metagenomic study of the oral microbiota by Illumina high-throughput sequencing. Lazarevic V et al. 2009.
The authors examined 753 species of oral microbiomes in three samples. More...
Lazarevic, Whiteson, Huse, Hernandez, Farinelli, Osterås, Schrenzel, Françoi Metagenomic study of the oral microbiota by Illumina high-throughput sequencing. Lazarevic V et al. 2009.Journal of Microbiological Methods
Polymorphisms in positional candidate genes on BTA14 and BTA26 affect carcass quality in beef cattle. Maques E et al. 2009.
Genetic variation in cattle can affect carcass quality. More...
Marques, Nkrumah, Sherman, Moor Polymorphisms in positional candidate genes on BTA14 and BTA26 affect carcass quality in beef cattle. Maques E et al. 2009.Journal of Animal Science
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Van Es MA et al. 2009.
Amyotrophic lateral sclerosis (ALS) is due to loss of motor neurons in several regions. More...
vanEs, Veldink, Saris, Blauw, vanVught, Birve, Lemmens, Schelhaas, Groen, Huisman, vanderKooiA, deVisser, Dahlberg, Estrada, Rivadeneira, Hofman, Zwarts, vanDoormaal, Rujescu, Strengman, Giegling, Muglia, Tomik, Slowik, Uitterlinden, Hendrich, Waibel, Meyer, Ludolph, Glass, Purcell, Cichon, Nöthen, Wichmann, Schreiber, Vermeulen, Kiemeney, Wokke, Cronin, McLaughlin, Hardiman, Fumoto, Pasterkamp, Meininger, Melki, Leigh, Shaw, Landers, Al-Chalabi, Brown, Robberecht, Andersen, Ophoff, vandenBerg Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Van Es MA et al. 2009.Nature Genetics
Identification of Nutrient-Responsive Arabidopsis and Rapeseed MicroRNAs by Comprehensive Real-Time Polymerase Chain Reaction Profiling and Small RNA Sequencing. Pant BD et al. 2009.
MicroRNAs can post-transcriptionally regulate gene expression, including that during nutrient limitation. More...
Pant, Musialak-Lange, Nuc, May, Buhtz, Kehr, Walther, Scheibl Identification of Nutrient-Responsive Arabidopsis and Rapeseed MicroRNAs by Comprehensive Real-Time Polymerase Chain Reaction Profiling and Small RNA Sequencing. Pant BD et al. 2009.Plant Physiology
A method for rapid, targeted CNV genotyping identifies rare variants associated with neurocognitive disease. Mefford HC et al. 2009.
This paper uses an adapted GoldenGate Assay on BeadXpress in conjunction with a new algorithm (SCOUT) to interrogate known and putative mutational "hotspots" in 1,010 subjects with intellectual disability. More...
Mefford, Cooper, Zerr, Smith, Baker, Shafer, Thorland, Skinner, Schwartz, Nickerson, Eichle A method for rapid, targeted CNV genotyping identifies rare variants associated with neurocognitive disease. Mefford HC et al. 2009.Genome Research
Human DNA methylomes at base resolution show widespread epigenomic differences. Lister et al. 2009.
The authors examined single-base level DNA methylation in embryonic stem cells (H1) and fibroblasts (IMR90), utilizing MethylC-Seq/ChIP-Seq and the Genome Analyzer II. More...
Human DNA methylomes at base resolution show widespread epigenomic differences. Lister et al. 2009.Nature