More Possibilities than Ever Before

Any application. Any study. Any budget.

Learn MoreTwo run modes. High output or rapid run. Flexibility to batch process multiple samples with high output in a single run, or get rapid results with fewer samples for time-critical studies.
Learn MoreOne run mode. High output. Generate the highest output and number of reads for batch processing multiple samples in a single run.

HiSeq 2500 HiSeq 1500
Run Mode High Output Rapid Run* High Output Rapid Run*
Output
(2 × 100 bp)
600 Gb 120 Gb 300 Gb 60 Gb
Run Time
(2 × 100 bp)
~11 days
~27 hours
~8.5 days
~27 hours
Cluster
Generation
cBot On board cBot On board
Paired-end
Reads
6 Billion 1.2 Billion 3 Billion
600 Million
Single Reads 3 Billion 600 Million 1.5 Billion 300 Million
Maximum
Read Length**
2 × 100 bp 2 × 150 bp 2 × 100 bp 2 × 150 bp
Quality
Scores***
> 85% (2 x 50 bp)
> 80% (2 x 100 bp)

HiSeq 2000 HiSeq 1000
Output (2 × 100 bp) 600 Gb 300 Gb
Run Time
(2 × 100 bp)
~11 days ~8.5 days
Cluster Generation cBot cBot
Paired-end Reads 6 Billion 3 Billion
Single Reads 3 Billion 1.5 Billion
Maximum
Read Length**
2 × 100 bp 2 × 100 bp
Quality Scores*** > 85% (2 x 50 bp)
> 80% (2 x 100 bp)

*Anticipated performance parameters, final specifications subject to change.
**Paired 150-cycle runs are supported only in the rapid run mode. Total output generated with 2 × 150 bp run anticipated to be up to 90 Gb per flow cell. Run time is approximately 40 hours.
***Based on an Illumina PhiX library at supported cluster densities.