Sequencing radically reinvented.

High-throughput scale. Desktop simplicity.

NextSeq 500 will transform your research. Enable new discoveries. And empower you to stay a step ahead. The first and only DNA and RNA sequencer to bring genomes, exomes and transcriptomes to your desktop, helping you see what you couldn’t see before, delivering better answers every day.

We designed NextSeq to be just right for you: the right combination of high-throughput speed, sample-size flexibility, push-button simplicity, and accessible affordability.

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  • The Next Evolution in Genomic Technology

    Learn why the NextSeq 500 desktop sequencer delivers more sequencing power directly to individual researchers than ever before.

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  • The First High-Throughput Desktop Sequencer

    See how the NextSeq 500 DNA and RNA sequencer combines high-throughput sequencing, speed, flexibility, and accuracy.

    Read the data sheet »
  • Key Applications with NextSeq

    Discover how the NextSeq 500 DNA and RNA sequencer performs whole-genome, exome, and transcriptome sequencing on a single platform.

    See our applications »
  • Webinars and Seminars

    Attend an Illumina presentation to learn how to use the NextSeq 500 desktop sequencer for any research application.

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  • Buyer’s Guide for Next-Generation Sequencers

    Choose the sequencing system that best meets your research goals and laboratory needs.

    Read the guide »
  • Meet the New Addition to Your Line-Up

    Power, speed, ease-of-use, flexibility, and connectivity make NextSeq 500 a great platform for RNA-Seq applications.

    Read the blog »

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