Sequencing systems for every lab, application, and scale of study.

From the power of the HiSeq X to the speed of MiSeq, Illumina has the sequencer that’s just right for you.
  MiSeq

MiSeq

Focused power. Speed and simplicity for targeted and small genome sequencing.
NextSeq 500

NextSeq 500

Flexible power. Speed and simplicity for everyday genomics.
HiSeq 2500

HiSeq 2500

Production power. Power and efficiency for large-scale genomics.
HiSeq X Sequencing System

HiSeq X*

Population power. $1,000 human genome and extreme throughput for population-scale sequencing.
Key applications
Small genome, amplicon, and targeted gene panel sequencing.
Everyday genome, exome, transcriptome sequencing, and  more.
Production-scale genome, exome, transcriptome sequencing, and more.
Population-scale human whole-genome sequencing.
Run mode N/A Mid-Output High-Output Rapid Run High-Output N/A
Flow cells processed per run
1 1 1 1 or 2 1 or 2 1 or 2
Output range 0.3-15 Gb 20-39 Gb 30-120 Gb 10-180 Gb 50-1000 Gb 1.6-1.8 Tb
Run time 5-55 hours 15-26 hours 12-30 hours 7-40 hours < 1 day - 6 days < 3 days
Reads per flow cell† 25 Million 130 Million 400 Million 300 Million 2 Billion 3 Billion
Maximum read length 2 × 300 bp 2 × 150 bp 2 × 150 bp 2 × 150 bp 2 × 125 bp 2 × 150 bp

 

* Specifications shown for an individual HiSeq X System. HiSeq X is only available as part of the HiSeq X Ten.
† Clusters passing filter.
‡ For MiSeq V3 Kits only.


Use our Sequencing Platform Comparison Tool to find the right sequencing system for your needs.


Read the Sequencing Portfolio Brochure to learn more about the systems.