Illumina’s GoldenGate Methylation solution is the first array-based platform that combines high sample throughput, high multiplexing, and single-site CpG resolution for DNA methylation profiling. The GoldenGate Assay can be used to simultaneously analyze the methylation status of up to 1,536 independent CpG sites per assay across 96 samples on either standard or custom content oligo sets. Several different control types are provided to ensure the highest quality data. Each bead type is represented with an average 30-fold redundancy to further enhance the assay’s accuracy and robustness. Following bisulfite conversion of the sample DNA, researchers can use this high-throughput assay with the standard GoldenGate Methylation Cancer Panel I or design their Custom Methylation Panels targeting CpG loci within a gene or region of interest.

Highlights

• High Multiplex Array Platform: Simultaneously analyze up to1,536 CpG sites
• Streamlined Workflow: 96 samples per Universal Array Matrix with the convenient three-day GoldenGate Assay workflow
• Flexible Content Selection: Standard and custom panels available