Next-generation sequencing (NGS) offers an opportunity for efficient DNA database sample turnaround. DNA profiling with NGS enables law enforcement investigations to more quickly identify suspects and links between forensic cases.
Millions of DNA profiles are curated in national and international DNA databases. These profiles assist law enforcement agencies in identifying perpetrators, linking multiple crime scenes, and resolving missing persons cases.
DNA databases around the world use polymerase chain reaction (PCR) followed by fluorescence-based length detection to analyze these DNA samples. This PCR technology has been in use, unchanged, for nearly two decades.
NGS gives labs more options for producing high-quality forensic DNA profiles. The single, all-in-one workflow can help labs process database samples more efficiently. Because Illumina sequencing technology analyzes multiple marker sets simultaneously, rather than sequentially, there is a faster turnaround.
NGS can provide more information than traditional methods. Using the MiSeq FGx System, DNA database laboratories can:
Illumina sequencing by synthesis (SBS) technology on the MiSeq FGx Forensic Genomics System streamlines forensic DNA databasing by combining multiple tests in a single analysis.
Our fully validated forensic NGS workflow includes a dedicated library prep kit, customized benchtop sequencing instrument, and an analytical software package to simplify your lab operations.
Click on the below to view products for each workflow step.
We recommend using your current DNA extraction and quantitation methods.
Assay approximately 200 genetic markers in a single test. Includes all reagents to prepare sequencing libraries from forensic DNA samples.
NGS enables genetic analysis for large numbers of globally relevant STR markers and dense SNP sets in a single test. Learn More »
Targeted sequencing of forensically relevant STR and SNP loci empowers you to generate leads, even on cold cases. Learn More »