With infertility rates on the rise and women waiting until later in life to have children, more patients are seeking help from assisted reproductive technologies. Although in vitro fertilization (IVF) techniques have dramatically improved, success rates remain low with only 30% to 40% of cycles resulting in live birth. Aneuploid embryos play a major role in IVF failure and miscarriages. As such, selection of euploid embryos through preimplantation genetic screening (PGS) via embryo biopsy has the potential to improve outcomes while reducing the instance of multiple gestations. For many years, the mainstay of PGS methods was fluorescence in situ hybridization (FISH) and more recently, polymerase chain reaction and DNA microarray. In 2014, a new methodology for PGS became available—next-generation sequencing (NGS).
Learn from Kumar Duraiswamy, Associate Director, Field Medical Affairs at Illumina, during this special 45 minute presentation about how NGS technology is empowering couples to make wiser choices.
The following topics will be covered: