Building a comprehensive sequencing portfolio with individual panels for each condition of interest presents numerous developmental and managerial complications. To help you overcome this challenge and streamline your sequencing portfolio while maximizing assay offerings, Illumina offers the TruSight One Sequencing Panel. TruSight One is a single, large sequencing panel targeting more than 4,800 genes and covering 12 Mb of genomic content. Combining TruSight One with the VariantStudio data analysis tool creates the simplest sample-to-report workflow that can replace dozens, if not hundreds, of small, individual sequencing panels and assays. The unmatched coverage uniformity of TruSight One facilitates high levels of multiplexing, enabling sequencing of trios on a single MiSeq flow cell and 36 samples on a single HiSeq flow cell.