Workflow

Simple workflow. Single-user operation.

System automation. Turnkey operation. The simple sequencing workflow enables even small labs to have sequencing capabilities rivaling those of genome centers. With the fastest and least labor-intensive workflow of any sequencing technology, your lab can generate highly accurate results in under a week. Automation frees you to complete groundbreaking studies in minimal time. Simplified process. Minimized hands-on time. It’s genomic power for everyone.

HiSeq Workflow


workflow

Applications


DNA Sequencing

Perform whole-genome or de novo sequencing, targeted resequencing, SNP discovery, and identification of copy number variations and chromosomal rearrangements using Illumina's massively parallel sequencing technology. Illumina sequencing features industry-leading read lengths, the highest raw read accuracy, and the flexibility of insert size and paired-end protocols, enabling the broadest range of genomic sequencing applications.

Whole Genome Sequencing – using the Illumina Genome Network

The Illumina Genome Network links researchers interested in conducting large whole human genome sequencing projects with leading institutes worldwide that provide highly economical and rapid turnaround access to Illumina sequencing.

Transcriptome Analysis

Explore the transcriptome like never before with Illumina sequencing. Characterize transcriptional activity and reveal the hidden world of RNA architecture without prior information using Illumina's unique combination of long and short reads and millions of counts. Analyze strand-specific mRNA, annotate coding SNPs, discover transcript isoforms, identify regulatory RNAs, characterize splice junctions and determine transcript abundance.

Gene Regulation Analysis

Accurately survey epigenetic interactions and their effects on gene expression central to many biological processes and disease states. Quantify in vivo protein-DNA interactions on a genome-wide scale using chromatin immunoprecipitation with Illumina sequencing technology (ChIP-Seq). Characterize the methylome to single base resolution by sequencing bisulfite-treated DNA.

Software

Open Architecture. Streamlined Analysis.

Genome Analyzer Analysis Workflow

Powerful Software. Easy-to-use Interface.

Our suite of integrated applications is built to go from image capture to interactive analysis in real time. Quickly and easily assess the success of your run. Customize your workflow engine with our flexible architecture. It's massive-scale data analysis, simplified.

Genome Analyzer Pipeline and CASAVA

  • Drives primary data analysis and transforms data into biologically relevant information.
  • Produces intensity scores, base calls with calibrated quality metrics, and quality-scored alignments.
  • Creates genomic builds, calls SNPs, and counts reads from data generated from one or more sequencing runs.
  • Enables easy customization for the throughput requirements of any lab.

GenomeStudio Software

  • Facilitates exploration of data from multiple genetic analysis applications.
  • Enables the comparison and correlation of data from all Illumina platforms.
  • Allows you to obtain a complete picture of the genome and identify potential disease targets.

Learn more about Illumina-evaluated software tools and other third-party Genome Analyzer data analysis solutions.