Production power.

Power and efficiency for large-scale genomics.

The HiSeq 2500 System is a powerful and efficient ultra-high-throughput sequencing system that supports the broadest range of applications and study sizes. Unrivaled data quality using Illumina's proven SBS chemistry has made the HiSeq 2500 the instrument of choice for all major genome centers and leading institutions throughout the world. New HiSeq v4 reagents allow for more reads and more data in less time.

Have questions about the HiSeq 2500? Contact a Sales Representative »

  • New HCS software now available

    Learn how the new HiSeq Control Software (v2.2.38) increases data quality for low diversity samples, now available for all HiSeq systems.

    Read technical note (PDF) »
    Download software »

  • Longer Reads in Rapid Mode
    HiSeq v2 Reagent Kits

    New HiSeq v2 reagents for rapid run mode increase read lengths up to 2x250 bp.

    See the new kits »
  • Sequencing Ancient DNA

    A long ago archaeological find yields new clues about Native American origins.

    Read article (PDF) »
  • Even More Data, Faster
    HiSeq v4 Reagent Kits

    Now available: HiSeq v4 reagents increase yield and throughput.

    See the new kits »
  • The Fastest Exome, Period.

    Go from sample to data in 2.5 days with the HiSeq 2500 ultra-high-throughput sequencer and Nextera Rapid Capture Exome.

    View video »
    See exome sequencing data »

  • Advancing Psychiatric Genetics Research

    See how HiSeq 2500 helps to identify genes that influence behavior.

    Read the article »