Cancer Genomics

I seek hope. Cancer genomics.

The expanding Illumina oncology portfolio of next-generation sequencing (NGS) and microarray technologies is revolutionizing cancer genomics research. Our simple, sample-to-data solutions deliver highly accurate, reproducible results for the discovery and analysis of cancer variants. Perform whole-genome, tumor/normal, RNA, and targeted sequencing in record time. Complete epigenetic analysis, germline risk assessment, and cytogenetics studies with ease. Through cancer community partnerships, we are enhancing our technologies with one goal in mind: To develop transformative solutions that deliver relevant cancer genomics information into the hands of translational and clinical researchers.

Germline Mutations

Germline mutations that predispose individuals to cancer can be detected through various approaches, ranging from genome-wide association studies (GWAS) to whole-genome and targeted gene sequencing. Learn more about detecting germline mutations »

Somatic Mutations

Tumor/normal sequencing studies are critical to distinguish between unique somatic mutations accrued by a tumor and germline mutations also present in the surrounding normal tissue. Illumina sequencers offer the speed and accuracy to detect these mutations. Learn more about detecting somatic mutations »

Gene Expression & Transcriptome Changes

Analyzing the entire cancer transcriptome or targeted transcripts with RNA-Seq allows researchers to detect significant expression changes, and to potentially identify genes associated with tumor progression. Learn more about RNA-Seq detection of gene expression & transcriptome changes »

Epigenetic Changes

Analysis of epigenetic changes in cancer cells, such as aberrant methylation and altered transcription factor binding, can provide key insights into tumorigenesis. Learn more about Illumina's NGS and array methods for detecting epigenetic changes »

Chromosomal Abnormalities

Genomic instability and chromosomal rearrangements are frequent features of cancer. Illumina offers both array- and sequencing-based approaches to identify gross chromosomal changes. Learn more about identifying chromosomal abnormalities »

Cancer Sequencing Methods

NGS methods enable researchers to perform whole-genome studies, targeted gene profiling, gene expression, and epigenetic studies on polyclonal tumor samples at a pace unheard of a few years ago. Learn more about cancer sequencing methods »

Cancer Data Analysis

The analysis of next-generation sequencing data from cancer samples can be challenging. Illumina offers a number of software options and analysis tools to simplify this process. Learn more about cancer data analysis »

Cancer Panel Comparison Tool

Cancer Panel Comparison Tool

Find the Cancer Panel that best fits your needs with this easy comparison table.
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Tumor/Normal Somatic Variant Calling

Evaluating Somatic Variant Calling

Identify true somatic variants even in low purity samples with this data analysis workflow.
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NGS: Solving the Cancer Puzzle

Illumina Sequencing Introduction

NGS-based cancer studies offer a deeper understanding of tumor biology.
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MiSeq: Comprehensive Profiling


The MiSeq sequencer enables comprehensive profiling of tumor samples. Interrogate a wider range of mutations than is possible with traditional technologies.
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Library Prep and Array Kit Selector

Product Selector

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Get help in choosing the right cancer research solution for you. Contact us »

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