BeadChip combining exceptional coverage of clinical research variants with optimized multiethnic, genome-wide content for genotype screening.
Sample throughput
Number of samples
Number of markers
The Infinium Global Diversity Array-8 Kit is the recommended replacement for the Infinium Multi-Ethnic Global, Multi-Ethnic AMR/AFR, and Multi-Ethnic EUR/EAS/SAS Kits, which have been discontinued. The Global Diversity Array is an updated version of the Multi-Ethnic Kits.
The Infinium Global Diversity Array 8-Kit (GDA) BeadChip is a powerful, cost-effective array with optimized, multiethnic, genome-wide content.
The GDA is the commercial version of the microarray trusted by this NIH precision medicine initiative, which will collect data from > 1M people to improve health outcomes.
A high-density SNP global backbone for cross-population imputation coverage of the genome enables polygenic risk score development and characterization of genetic architecture in diverse populations.
The robust genome-wide scaffold was designed to tag common and low-frequency variants in global populations through collaborations with the Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA) and Population Architecture using Genomics and Epidemiology (PAGE). Content includes > 1K whole-genome sequences of African ancestry and populations throughout the Americas.
| Assay type | Infinium LCG |
|---|---|
| Automation capability | Liquid Handling Robots, Automated Array Loader |
| Description | The 8-sample Infinium Diversity Array provides targeted coverage of more than 4800 key genes across the genome. Approximately 1.8M markers are included on the BeadChip for high exonic coverage in regions of disease relevance, providing highly accurate copy number variation calls, and an average resolution of 1.5Mb. |
| Input quantity | 200 ng DNA |
| Instruments | iScan System |
| Method | Genome-Wide Genotyping Array |
| Nucleic acid type | DNA |
| Number of markers |
1,825,277 fixed markers. Custom marker add-on capacity: Up to 175K. |
| Number of samples | 8 samples per array |
| Sample throughput | ~1728 samples per week |
| Specialized sample types | Blood, FFPE Tissue, Buccal Swabs, Saliva |
| Species category | Human |
| Technology | Microarray |
| Variant class | Single nucleotide polymorphisms (SNPs), Loss of heterozygosity (LOH), Chromosomal abnormalities, Structural variants, Copy number variants (CNVs) |
Match your chosen kit size to the number of samples you run at a time. Each kit is processed as a single batch and is not designed to be divided across multiple experiments. If you are processing several low-throughput batches, order multiple small kits.
You can choose to customize your content using DesignStudio or select from a list of optional add-on content available as consortia boosters. Booster add-on content is available for:
Neurodegenerative diseases (~75K SNPs)
Oncology (~90K SNPs)
Carrier screening (partnership with Igentify for interpretation)
Check with your sales rep to confirm availability and pricing.
The Infinium Global Diversity Array-8 Kit is a powerful, cost-effective BeadChip with optimized, multiethnic genome-wide content for population-scale genetic studies, variant screening, and precision medicine research.
Infinium Global Diversity Array
Large-scale genotyping with microarrays can identify variants associated with disease risk in large cohorts or populations.
Genome-wide association studies
Genome-wide association studies (GWAS) enable the discovery and characterization of genetic variants associated with disease.
Pharmacogenomics studies how variations in the human genome affect our response to medications, helping to reduce adverse drug reactions and medical costs.
| Infinium Global Diversity Array-8 Kit | Infinium Global Diversity Array with Enhanced PGx | Infinium Global Screening Array-24 Kit | Infinium Global Diversity Array with Carrier Screening Content-8 v2.0 Kit | Infinium Global Diversity Array with Cytogenetics-8 | |
|---|---|---|---|---|---|
| Assay type | Infinium LCG | Infinium HTS | Infinium LCG | ||
| Automation capability | Liquid Handling Robots, Automated Array Loader | Liquid Handling Robots, Automated Array Loader | Liquid Handling Robots, Automated Array Loader | Liquid Handling Robots, Automated Array Loader | |
| Description | The 8-sample Infinium Diversity Array provides targeted coverage of more than 4800 key genes across the genome. Approximately 1.8M markers are included on the BeadChip for high exonic coverage in regions of disease relevance, providing highly accurate copy number variation calls, and an average resolution of 1.5Mb. |
The Infinium Global Diversity Array with Enhanced PGx is built on an 8-sample BeadChip and contains > 1.9M markers. It is the most comprehensive genotyping microarray commercially available for pharmacogenomic (PGx) research, and also supports disease and diversity studies and other applications. |
The Infinium Global Screening Array-24 Kit is an economical genotyping array for population-scale genetics, translational research, variant screening studies, and precision medicine research, combining optimized multiethnic genome-wide content, curated clinical research variants, and QC markers. |
The Infinium Global Diversity Array with Carrier Screening Content-8 BeadChip expands carrier screening studies and features over 45K high-impact markers on the Global Diversity Array backbone. The Igentify Analyze software simplifies analysis, enabling high detection rates for key disorders. | The 8-sample Infinium Global Diversity Array with Cytogenetics-8 provides extensive targeted coverage of more than 4800 key genes across the genome. Approximately 1.8M markers are included on the BeadChip for high exonic coverage in regions of disease relevance, providing highly accurate copy number variation calls, and an average resolution of 1.5Mb. |
| Input quantity | 200 ng DNA | 200 ng DNA | 200 ng DNA | 200 ng DNA | |
| Instruments | iScan System | iScan System | iScan System | iScan System | |
| Method | Genome-Wide Genotyping Array | Genome-Wide Genotyping Array, High-Throughput Genotyping Array | Genome-Wide Genotyping Array | Genome-Wide Genotyping Array, Cytogenomic Array | |
| Nucleic acid type | DNA | DNA | DNA | DNA | |
| Number of markers |
1,825,277 fixed markers. Custom marker add-on capacity: Up to 175K. |
1,933,117 markers in total; custom add-on capacity of 175,000 |
654,027 fixed markers. Custom marker add-on capacity: Up to 100K. |
||
| Number of samples | 8 samples per array | 8 samples per array | 24 samples per array | 8 samples per array | 8 samples per array |
| Sample throughput | ~1728 samples per week | ~1728 samples per week | ~5760 samples per week | ||
| Specialized sample types | Blood, FFPE Tissue, Buccal Swabs, Saliva | Blood, FFPE Tissue, Buccal Swabs, Saliva | Blood | Blood, FFPE Tissue, Buccal Swabs, Saliva | |
| Species category | Human | Human | Human | Human | |
| Technology | Microarray | Microarray | Microarray | ||
| Variant class | Single nucleotide polymorphisms (SNPs), Loss of heterozygosity (LOH), Chromosomal abnormalities, Structural variants, Copy number variants (CNVs) | Single nucleotide polymorphisms (SNPs), Structural variants, Copy number variants (CNVs) | Single nucleotide polymorphisms (SNPs), Structural variants, Copy number variants (CNVs) | Single nucleotide polymorphisms (SNPs), Loss of heterozygosity (LOH), Chromosomal abnormalities, Copy number variants (CNVs) |
Library Prep and Array Kit Selector
Find the right sequencing library preparation kit or microarray for your needs. Filter by method, species, and more. Compare, share, and order kits.
Identify sequencing panels or microarrays that target your gene(s) of interest.
DesignStudio Custom Assay Design Tool
DesignStudio is a web-based assay design tool to help researchers design and order custom sequencing probes, or create custom genotyping array assays.
Inner pie shows the proportion of the array selected for genome-wide coverage, clinical research, and quality control (QC). Outer ring shows the weighted reference global allele frequency for unique variants present in 1kGP.2 Variants not in 1kGP are labeled. Counts represent unique variants.
Content was expertly selected from scientifically recognized databases to create a highly informative array for clinical research applications. Variant counts may be subject to change.
Selected based on CPIC guidelines and PharmGKB database.3 PGx public database variants, variants annotated in PharmGKB, PharmVar, CPIC; Genome-wide PGx coverage, includes markers located in an extended ADME genes or CPIC level A genes including targeted imputation tag SNPs and CPIC level A CNV tags.
(A) Variants sorted by range of pathology classifications according to ClinVar American College of Medical Genetics and Genomics (ACMG) annotations. (B) Global Diversity Array clinical research content by category within the ClinVar database. Variant counts may be subject to change.
QC variants on the array enable various capabilities for sample tracking such as sex determination, continental ancestry, human identification, and more.
The Illumina Polygenic Risk Score solution is a comprehensive, easy-to-implement, and versatile genomic analysis tool set for translational researchers.
Infinium Global Diversity Array-8 v1.0 Kit (16 samples)
20031669
The Global Diversity Array (GDA) is a high-density, customizable genotyping tool built in collaboration with the All of Us U.S. Precision Medicine Initiative. The GDA delivers unparalleled data quality, powerful multi-ethnic coverage, and extensive coverage of clinically relevant variants and pharmacogenomics markers. Each kit contains two BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 16 DNA samples.
List Price:
Discounts:
Infinium Global Diversity Array-8 v1.0 Kit (48 Samples)
20031810
The Global Diversity Array (GDA) is a high-density, cutomizable genotyping tool built in collaboration with the All of Us U.S. Precision Medicine Initiative. The GDA delivers unparalleled data quality, powerful multi-ethnic coverage, and extensive coverage of clinically relevant variants and pharmacogenomics markers. Each kit contains six BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 48 DNA samples.
List Price:
Discounts:
Infinium Global Diversity Array-8 v1.0 Kit (96 samples)
20031811
The Global Diversity Array (GDA) is a high-density, customizable genotyping tool built in collaboration with the All of Us U.S. Precision Medicine Initiative. The GDA delivers unparalleled data quality, powerful multi-ethnic coverage, and extensive coverage of clinically relevant variants and pharmacogenomics markers. Each kit contains twelve BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 96 DNA samples.
List Price:
Discounts:
Infinium Global Diversity Array-8 v1.0 Kit (384 Samples)
20031812
The Global Diversity Array (GDA) is a high-density, customizable genotyping tool built in collaboration with the All of Us U.S. Precision Medicine Initiative. The GDA delivers unparalleled data quality, powerful multi-ethnic coverage, and extensive coverage of clinically relevant variants and pharmacogenomics markers. Each kit contains 48 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 384 DNA samples.
List Price:
Discounts:
Infinium Global Diversity Array-8+ v1.0 Kit (16 Samples)
20031813
The Global Diversity Array (GDA) is a high-density, customizable genotyping tool built in collaboration with the All of Us U.S. Precision Medicine Initiative. The GDA delivers unparalleled data quality, powerful multi-ethnic coverage, and extensive coverage of clinically relevant variants and pharmacogenomics markers. Each kit contains two BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 16 DNA samples.
Infinium Global Diversity Array-8+ v1.0 Kit (48 Samples)
20031814
The Global Diversity Array (GDA) is a high-density, customizable genotyping tool built in collaboration with the All of Us U.S. Precision Medicine Initiative. The GDA delivers unparalleled data quality, powerful multi-ethnic coverage, and extensive coverage of clinically relevant variants and pharmacogenomics markers. Each kit contains six BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 48 DNA samples.
Infinium Global Diversity Array-8+ v1.0 Kit (96 Samples)
20031815
The Global Diversity Array (GDA) is a high-density, customizable genotyping tool built in collaboration with the All of Us U.S. Precision Medicine Initiative. The GDA delivers unparalleled data quality, powerful multi-ethnic coverage, and extensive coverage of clinically relevant variants and pharmacogenomics markers. Each kit contains twelve BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 96 DNA samples.
Infinium Global Diversity Array-8+ v1.0 Kit (384 Samples)
20031816
The Global Diversity Array (GDA) is a high-density, customizable genotyping tool built in collaboration with the All of Us U.S. Precision Medicine Initiative. The GDA delivers unparalleled data quality, powerful multi-ethnic coverage, and extensive coverage of clinically relevant variants and pharmacogenomics markers. Each kit contains 48 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 384 DNA samples.
Infinium® Assay: An Introduction – Customer Site
20015273
Three-day, hands-on instruction at customer site to familiarize users with the essential steps in the Infinium protocol. Course provides hands-on training in sample and BeadChip preparation, sample scanning using the iScan System, and primary data evaluation and analysis using array analysis software.
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The Infinium GDA delivers the most cost-effective per variant coverage within the Illumina human array portfolio and is ideal for precision medicine programs aiming to maximize return on genotyping investments. The Infinium GDA with Enhanced PGx Content is the most comprehensive microarray available for PGx research versus all commercially available microarrays.1 See more differences on the Infinium GDA with Enhanced PGx Content product page.
A polygenic risk score (PRS) represents the total number of genetic variants an individual has that increase their risk of developing a certain complex condition or disease. The Global Diversity Array 8-Kit enables researchers to develop PRS assessment in diverse populations. Learn more about polygenic risk scores.
Advanced chemistry, optics, and informatics combine to deliver exceptional speed and data quality, outstanding throughput and scalability.
Optimized reagent kit that provides increased cluster density and read length, improving sequencing quality scores compared to earlier versions.
Enable CGP with a large pan-cancer panel covering all major variant classes plus gene signatures (TMB, MSI, and HRD) from FFPE tissue.
A fast, integrated workflow for preparing libraries for use in a wide range of sequencing applications.
A comprehensive microarray solution that enables production-scale genotyping of up to 100,000 single- or multi-species custom variants for non-human, and 50,000 custom variants for human.
Robust methylation profiling microarray providing extensive coverage of CpG islands, genes, and enhancers for epigenome-wide association studies.
Data calculations on file. Illumina, Inc. March 2021.
The 1000 Genomes Project. 1000 genomes.org. Accessed August 24, 2021.
PharmGKB, The Pharmacogenomics Knowledgebase. www.pharmgkb.org. Accessed August 4, 2021.
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