The BovineSNP50 v2 BeadChip contains 54,609 highly informative SNPs uniformly distributed across the entire genome of major cattle breed types, empowering applications such as genome-wide enabled selection, identification of quantitative trait loci, evaluation of genetic merit of individuals, and comparative genetic studies.

This BeadChip was developed by Illumina in collaboration with the USDA-ARS, University of Missouri, and the University of Alberta. More than 24,000 SNP probes target novel SNP loci that were discovered by Illumina sequencing of three pooled populations of economically important beef and dairy cattle. Additional content is derived from publicly available sources such as the bovine reference genome, Btau, and the Bovine HapMap Consortium data set. All SNP probes have been validated in 19 common beef and dairy breeds. This product targets evenly distributed SNPs that are polymorphic across the breeds tested and provides an average probe spacing of 49.4kb and a median spacing of 36.9kb.

The BovineSNP50 BeadChip is a multi-sample genotyping panel powered by Illumina's Infinium HD Assay. This assay provides the industry's highest call rates, allows for flexible content deployment, and enables the detection and measurement of copy number variation.

  • This 24-sample BeadChip represents the highest density genotyping solution for characterizing the genome in dairy and beef cattle
  • The PCR-free, single tube sample preparation1,2 significantly reduces labor and potential sample handling errors
  • Laboratory Information Management System (LIMS) and robotic automation are available to accurately and efficiently track samples throughout analysis

For high-throughput, cost-effective genetic screening, the BovineSNP50 BeadChip features more than 54,000 evenly spaced SNP probes spanning the bovine genome.

References

  1. Gunderson KL, Steemers FJ, Lee G, Mendoza LG, Chee MS (2005) A genome-wide scalable SNP genotyping assay using microarray technology. Genet 37: 549–554.
  2. Steemers FJ, Chang W, Lee G, Barker DL,Shen R, et al. (2006) Whole-genome genotyping with the single-base extension assay. Nat Methods 3: 31–33.

System Compatibility

HiScan
HiScanSQ
iScan

Product Literature

BovineSNP50 Genotyping BeadChip

Catalog IDs: WG-450-2001, WG-450-2002, WG-450-2003

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