| System: | iScan, iScanSQ, BeadStation, BeadArray Reader |
|---|---|
| Technology: | BeadArray |
| Assay: | Infinium DNA Analysis Assay |
| Applications: | Focused Genotyping |
| Species: | Bovine |
| Contents: | Each package contains 4 to 96 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling, and detecting 48 to 1152 samples |
The BovineSNP50 DNA Analysis BeadChip was developed by Illumina in collaboration with the USDA-ARS, University of Missouri, and the University of Alberta. The BeadChip contains 54,001 highly informative SNPs uniformly distributed across the entire genomes of major cattle breed types. All SNP probes on have been validated in 19 common beef and dairy breeds. This empowers applications such as genome-wide enabled selection, identification of quantitative trait loci, evaluation of genetic merit of individuals, and comparative genetic studies.
More than 24,000 SNP probes target novel SNP loci that were discovered by sequencing three pooled populations of economically important beef and dairy cattle using Illumina's Genome Analyzer. Additional content is derived from publicly available sources such as the bovine reference genome, Btau1, and the Bovine HapMap Consortium data set. This product targets evenly distributed SNPs that are polymorphic across the breeds tested and provides an average probe spacing of 51.5kb and a median spacing of 37.3kb.
The BeadChip is a multi-sample genotyping panel powered by Illumina's Infinium HD Assay. This assay provides the industry's highest call rates, allows for flexible content deployment, and enables the detection and measurement of copy number variation.
Focused genotyping supports a variety of applications such as candidate-gene studies in cancer, cardiovascular disease, and admixture mapping. Illumina also works closely with major animal consortia to develop genome-wide genotyping products for non-human organisms, including both animal and plant species.
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