A new version of the Infinium CoreExome-24 BeadChip, v1.4, is available. The content does not vary significantly from the v1.3 BeadChip, with only a few minor SNP changes (see details).

Infinium CoreExome-24 Kit

This DNA microarray kit delivers genome-wide SNP and genetic variant information for genetic studies, especially large-scale human genotyping studies. Read More...
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Infinium CoreExome-24 v1.4 Kit (48 Samples)

20039222

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Infinium CoreExome-24 v1.4 Kit (288 Samples)

20039223

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Infinium CoreExome-24 v1.4 Kit (1152 Samples)

20039224

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Infinium CoreExome-24+ v1.4 Kit (48 Samples

20039214

Infinium CoreExome-24+ v1.4 Kit (288 Spl)

20039215

Infinium CoreExome-24 v1.4 Kit (1152 Samples)

20039216

Product Highlights

The customizable Infinium CoreExome-24 BeadChip offers an economical way to perform and support large genetic studies, especially large-scale genotyping studies. This array can also be used to quickly and easily obtain baseline sample data sets for a variety of downstream applications, including common variant, sex confirmation, mitochondrial DNA, ancestry, loss-of-variant, indel, and copy number variation (CNV) studies.

Developed in collaboration with several leading research institutions, the Infinium CoreExome-24 BeadChip includes all the tag SNPs found on the Infinium Core-24 BeadChip, plus over 240,000 markers from the Infinium Exome-24 BeadChip. For greater flexibility, the Infinium CoreExome-24+ version of the BeadChip can be customized to include up to 100,000 additional markers.

The Infinium CoreExome-24 BeadChips use the Infinium high-throughput screening (HTS) 24-sample format, enabling high content flexibility, throughput capacity, and genotyping accuracy. When combined with the proven iScan System, these BeadChips deliver affordable, high-quality, genome-wide information across diverse world populations.

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Specifications

Product Comparison

Infinium CoreExome-24 Kit Infinium Global Screening Array-24 Kit Infinium OmniExpressExome-8 Kit Infinium Omni2.5Exome-8 Kit Infinium Omni5Exome-4 Kit
Automation Capability Automated Array Loader, Liquid Handling Robots Automated Array Loader, Liquid Handling Robots Automated Array Loader, Liquid Handling Robots Automated Array Loader, Liquid Handling Robots Automated Array Loader, Liquid Handling Robots
Description Includes all of the tag SNPs found on the Infinium Core-24 BeadChip, plus over 240,000 markers from the Infinium Exome-24 BeadChip, with the capacity to add up to 100,000 semi-custom markers for economical large-scale genotyping studies. An economical next-generation genotyping array that enables population-scale genetics, translational research, variant screening studies, and precision medicine research by combining highly optimized multiethnic genome-wide content, curated clinical research variants, and QC markers. Offers over 274,000 functional exonic markers while delivering high coverage of putative functional exonic variants selected from over 12,000 individual exome and whole-genome sequences, for studying novel associations with traits and diseases. Combines >2.5 million tag SNPs from the HapMap and 1000 Genomes projects (>2.5%MAF) with >240,000 markers from the Infinium Exome-24 BeadChip array, to enable genome-wide variation studies while maximizing coverage of functional exonic SNPs. A high-density array that provides coverage of common, intermediate, and rare SNPs using functional exonic content, for genome-wide genotyping and copy number variation studies.
Number of Markers Fixed markers: 567,218, Custom marker add-on capacity: Up to 100,000 (with + kit versions) Fixed markers: ~ 654,027
Custom marker add-on capacity: Up to 100,000
Fixed markers: 958,497, Custom marker add-on capacity: Up to 30,000 Fixed markers: 2,618,000, Custom marker add-on capacity: None Fixed markers: 4,548,474, Custom marker add-on capacity: None
Number of Samples 24 samples per array 24 samples per array 8 samples per array 8 samples per array 4 samples per array
Sample Throughput ~2304 samples per week (estimate for 1 iScan System, 1 AutoLoader 2.x, 2 Infinium Automated Pipetting Systems, and a 5-day work week) ~5760 samples/week max per iScan (throughput and scan times may vary based on laboratory and system configurations.) ~960 samples per week (estimate for 2 iScan Systems, 1 AutoLoader 2.x, 2 Infinium Automated Pipetting Systems, and a 5-day work week) ~1728 samples/week per iScan (max throughput and scan time may vary based on lab and system configurations) ~544 samples per week (estimate for 2 iScan Systems, 1 AutoLoader 2.x, 3 Infinium Automated Pipetting Systems, and a 5-day work week)
Species Category Human Human Human Human Human

Method-Specific Workflow Example

 

Case Studies

Scanning Population-Based Biobanks to Identify a Rare Gene Variant for Myocardial Infarctions

The HUNT Biobank and Lifandis AS provide access to biological samples and corresponding clinical data from more than 250,000 individuals in the Norwegian population using Illumina off-the-shelf and custom Infinium HumanExome BeadChips.

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Customizing Genetic Testing in Japan and Southeast Asia

Genesis Healthcare uses the HumanCoreExome+ Array to provide direct-to-consumer genetic testing services that promote health and wellness.

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Gene Panel and Array Finder

Microarrays are a valuable tool for variant detection. With the Gene Panel and Array Finder, you can search human microarrays by genomic location or variant ID, or find arrays for other species.

Find the Right Panel
Gene Panel and Array Finder

The HumanCoreExome-24 BeadChip Kit has been renamed to Infinium CoreExome-24 Kit. Kits with either name on the label contain the same quality reagents and follow the same workflow.

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