Driving breakthroughs in cancer research

Accurate next-generation sequencing methods for a comprehensive view of cancer-causing mutations

Cancer Sequencing Methods

Cancer sequencing using next-generation sequencing (NGS) methods provides more information in less time compared to traditional single-gene and array-based approaches. With NGS, researchers can perform whole-genome studies, targeted gene profiling, tumor-normal comparisons, and more. NGS also offers the sensitivity to detect rare somatic variants, tumor subclones, and circulating DNA fragments.

Oncology
Cancer Whole-Genome Sequencing

See a comprehensive view of the unique mutations present in tumor tissue.

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Cancer Exome Sequencing

Cost-effectively identify cancer-associated coding variants.

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Targeted Cancer Sequencing

Focus on sequencing a set of genes or genomic regions with known cancer associations.

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Cancer RNA Sequencing

Identify novel transcripts or determine which genes are overexpressed or underexpressed in tumors.

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Circulating Tumor DNA (ctDNA) Sequencing

NGS offers the sensitivity and specificity that researchers need to detect low levels of ctDNA.

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Featured Cancer Sequencing Research

 
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Exploring the Genetic Basis of Oral Cancer

Researchers use various cancer sequencing methods to uncover somatic variants, methylation changes, and other genomic alterations associated with a deadly oral cancer.

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Searching for Cancer Driver Genes
Searching for Cancer Driver Gene Expression Clues

Whole-genome sequencing of ctDNA samples enables researchers to analyze nucleosome patterns and infer the gene expression status of cancer driver genes.

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Role of Long Non-Coding RNA in Cancer
Deciphering the Role of Long Non-Coding RNA in Cancer

Researchers utilize RNA sequencing to reveal how lncRNAs could be used to identify, measure, and treat cancer.

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Methods Guide

Access the information you need—from BeadChips to library preparation for genome, transcriptome, or epigenome studies to sequencer selection, analysis, and support—all in one place. Select the best tools for your lab with our comprehensive guide designed specifically for research applications.

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Methods Guide
TruSight Oncology Family Grows with Liquid Biopsy and High-Throughput Assays
TruSight Oncology Family Grows with Liquid Biopsy and High-Throughput Assays

Providing customers with a versatile, scalable, sample-to-report workflow

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Using Genetic Testing to Advance Cancer Care
Using Genetic Testing to Advance Cancer Care

Australia-based XING Cancer Care is analyzing tumor DNA with the goal of improving cancer treatment.

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The Weizmann Institute Uses NovaSeq to Drive Single Cell Research
The Weizmann Institute Uses NovaSeq to Drive Single Cell Research

By analyzing one cell at a time, Professor Amit is improving our understanding of biological systems in health and disease

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See More Cancer-Specific Content and Products

The user-friendly "Recommended Links" feature allows you to easily find content and products relevant to cancer research and/or a variety of other fields. You can access this option from the top of any illumina.com page.

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High-Throughput Genomics Technologies for Cancer Research

Learn how NGS-based cancer sequencing can provide a deeper understanding of tumor biology.

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Sequencing Limited or Low-Quality Tumor Samples

Find solutions that facilitate analysis of FFPE and limited (needle biopsy or aspirate) tumor DNA.

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Detection of Actionable Alterations in Tumors

Wagle et al. demonstrate detection of genomic alterations in tumor samples by high-throughput sequencing.

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Cancer Research Review

An overview of recent cancer research publications featuring Illumina technology.

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Cancer and Immune System Research Review

An overview of recent research publications exploring the interaction between tumor cells and the immune system.

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