Unlock a broad range of applications with one powerful instrument
Science moves fast, and so do you. Access applications ranging from targeted sequencing to data-rich multiomics applications including whole-exome, spatial transcriptomics, and single-cell sequencing. Scalability to help you prepare for the future today.
Accelerated discovery. Easier than ever.
Experience our simplest workflow yet with easier run setup, time-saving dry instrumentation, and DRAGEN on-board for no additional cost, providing accurate and efficient secondary analysis, up to 6x faster. Now with losless genomic compression, saving up to 80% on storage costs.
See the system in your lab
Frame the QR code with your smartphone for a virtual view of the system on-location in your lab environment.
Sequencing flexibility for the applications you need
The NextSeq 1000 and NextSeq 2000 are redesigned from the ground up. Their flexibility, affordability, and scalability help both new and experienced users achieve fast turnaround times and reduced operating costs. With the wide range of available flow cells, they support a variety of applications including:
Single-Cell Gene Expression
Examine the transcriptomes of individual cells for a high-resolution view of cell-to-cell variation.
Whole-Exome Sequencing
Efficiently identify coding variants across a broad range of applications, including population genetics, genetic disease, and cancer studies.
Shotgun Metagenomics
Comprehensively sample all genes in all organisms present in a given complex sample.
Spacial Transcriptomics
Pinpoint predictive cellular state and their spatial localization to understand the influence of the cellular and spatial architecture on the microenvironment.
Total RNA Squencing
Analyze both coding RNA and multiple forms of noncoding RNA for a comprehensive view of the transcriptome.
Infectious Disease Research
Infectious Disease Research Description: A universal, culture-free method for infectious disease characterization and surveillance that may be used with viruses, bacteria, fungi, and parasites, and can replace the need for multiple tests.
Expand Your Access to More Data and Applications
High Intensity Sequencing
High-intensity sequencing applications generate dramatically more data for more impactful insights.
Multiomics
Perform transformative science with access to multiple emerging high-throughput omics applications.
Efficient and Cost-Effective
Researchers talk about their experience using the NextSeq 1000 and NextSeq 2000 Sequencing Systems.
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A fast and intuitive workflow to maximize your time and resources
The NextSeq 1000 and NextSeq 2000 Systems support a wide range of methods such as exome sequencing, target enrichment, single-cell profiling, transcriptome sequencing, and more. With DRAGEN onboard, the systems offer an intuitive workflow with load-and-go ease and push-button bioinformatics analysis.
Prep
Support for a broad range of conventional and emerging applications
Sequence
Access best-in-class benchtop sequencing accuracy, performance, and throughput
Analyze
Rapid, accurate analysis in the cloud and on-instrument
System Specifications
10-360 Gb*
output range100 M-2.4 B**
reads per run2 x 300 bp
max read length*Specifications based on Illumina PhiX control library at supported cluster densities.
**100 M - 1.2 B single reads per run. 200 M - 2.4 B paired-end reads per run.
Recommended Products
NextSeq 1000/2000 Reagents
NextSeq 1000/2000 reagent kits contain a reagent cartridge, flow cell, and resuspension buffer. Multiple flow cell configurations offer adjustable output based on project needs.
Illumina DNA PCR-Free Prep
A high-performing, fast, and integrated workflow for sensitive applications such as human whole-genome sequencing.
TruSeq Small RNA Library Preparation Kits
These kits provide a simple, cost-effective solution for generating miRNA and small RNA sequencing libraries directly from total RNA, for any species.
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