TruSeq Methyl Capture EPIC Library Prep Kit

This kit combines next-generation sequencing with epigenetic insights to accelerate biomarker discovery and understand methylation’s role in gene regulation.Read More...
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TruSeq-Methyl Capture EPIC Library Prep Kit (12 samples, 4 indexes)

FC-151-1002

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TruSeq-Methyl Capture EPIC Library Prep Kit (48 samples, 12 indexes)

FC-151-1003

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Product Highlights

Targeted methylation sequencing (Methyl-Seq) offers a balanced, cost-effective choice between whole-genome bisulfite sequencing and methylation arrays that can support both screening and biomarker discovery study objectives.1 TruSeq Methyl Capture EPIC Library Prep supports researchers seeking a deeper understanding of the role of methylation in gene regulation.

Comprehensive methylation-site content: Offers significantly higher coverage of emerging epigenetic regions of interest compared to other Methyl-Seq kits currently on the market (See Supporting Data section, Epigenetic Regions Covered).

Maximize discovery power, minimize cost: Efficiently query differentially methylated bases to conserve research dollars.

Convenient kit configuration: Includes bisulfite conversion, library prep, target enrichment, and purification reagents in a single kit for hassle-free ordering.

User-friendly data analysis: Analyze sequence data in BaseSpace Sequence Hub with methylation apps designed for biologists.

Specifications

Method-Specific Workflow Example

 

Supporting Data and Figures

 

This kit requires a PCR enzyme kit such as the Kapa Hifi Uracil+ (Cat No. KK2801), available separately.

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Infinium MethylationEPIC Kit

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Targeted panel that measures expression levels of >20,000 human RefSeq genes.


AmpliSeq for Illumina Comprehensive Cancer Panel

Targeted panel investigating the exonic regions of 409 genes with known associations to cancer.


References
  1. Masser DR, Stanford DR, and Freeman WM. Targeted DNA methylation analysis by next-generation sequencing. J Vis Exp. 2015; (96).
  2. Agilent SureSelect MethylSeq target regions. Accessed 14 June 2016.
  3. Roche Nimblegen CpGiant target regions. Accessed 14 June 2016.