Detailed insight into complex genomes

Delivering high-quality data for long-read applications

Long-Read Sequencing Technology

Long-read sequencing is a highly accurate approach that can be used to:

  • Sequence traditionally challenging genomes, such as those containing stretches of highly repetitive elements
  • Generate long reads for de novo assembly and genome finishing applications
  • Perform whole human genome phasing to identify co-inherited alleles, haplotype information, and phase de novo mutations
Push-Button Informatics

Our user-friendly software tools make NGS data analysis accessible to any researcher, regardless of bioinformatics experience.

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Long-read sequencing technology has the potential to improve the efficiency and accuracy of many existing DNA sequencing applications while increasing the coverage of clinically important genes.

These advantages allow for the phased re‐sequencing of human genomes and rapid de novo sequencing of plant and animal genomes.

The long reads produced typically span more than one heterozygous SNP in the phasing application. The technology simplifies de novo sequencing because large repeat regions in the DNA fragments can easily be spanned.

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The Illumina Long-Read Applications Ecosystem is a group of partnerships dedicated to ensuring the delivery of high-quality data for fully featured genomes, including phasing, detection of structural variants, and de novo assembly of all species.

The combination of our core sequencing technology, along with our partners’ linked-read preps, assembly protocols, and analysis pipelines, are allowing Illumina to bring advanced long-read application solutions to the market. The Illumina Long-Read Ecosystem leverages the following partner products and services:

Long-Read Sequencing Partnerships
10x Genomics
10x Genomics
www.10xgenomics.com

10x Genomics Chromium genome and exome products make phasing and structural variant information accessible to human health researchers.

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Dovetail Genomics
www.dovetailgenomics.com

The Dovetail Genomics assembly service (full assembly and assembly improvements), available for a wide range of genomes, leverages its Chicago library prep and proprietary analysis pipeline.

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NRGene
www.nrgene.com

The NRGene DeNovoMagic analysis product delivers computational tools to facilitate optimal trait discovery for seed companies, animal breeders, and academia.

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Rare Disease Genomics

Understanding the variants associated with rare diseases can help researchers pinpoint the causes of genetic disorders.

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Cancer Whole-Genome Sequencing

Get a comprehensive base-by-base view of the unique genomic abnormalities in cancer.

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Plant and Animal Sequencing

Sequencing can help identify novel species, improve our food supply, and ensure a sustainable environment.

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Explore the NovaSeq 6000 System

Scalable throughput and flexibility for virtually any genome, sequencing method, and scale of project.

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Explore the NovaSeq Series
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