Illumina sequencing platforms

Our innovative next-generation sequencing (NGS) platforms deliver exceptional data quality and accuracy, at a massive scale. From benchtop to production-scale sequencing systems, you’ll find the right platform to advance your research.

Sequencing Platforms

 
MiniSeq System
MiSeq Series
NextSeq Series
Popular Applications & Methods
Key Application Key Application Key Application
Large Whole-Genome Sequencing (human, plant, animal)      
Small Whole-Genome Sequencing (microbe, virus)      
Exome Sequencing      
Targeted Gene Sequencing (amplicon, gene panel)      
Whole-Transcriptome Sequencing      
Gene Expression Profiling with mRNA-Seq      
Targeted Gene Expression Profiling      
miRNA & Small RNA Analysis      
DNA-Protein Interaction Analysis      
Methylation Sequencing      
16S Metagenomic Sequencing      
How to Choose a Benchtop Sequencer

This Benchtop Sequencing Buyer’s Guide has tips to help you make a smooth transition to next-generation sequencing and select the best benchtop sequencing system to achieve your research objectives.

Read Benchtop Buyer's Guide
Run Time 4–24 hours 4–55 hours 12–30 hours
Maximum Output 7.5 Gb 15 Gb 120 Gb
Maximum Reads Per Run 25 million 25 million* 400 million
Maximum Read Length 2 × 150 bp 2 × 300 bp 2 × 150 bp
  Explore MiniSeq Request Pricing Compare MiSeq Request Pricing Compare NextSeq Request Pricing
 
NextSeq Series
HiSeq Series
HiSeq X Series
NovaSeq Series
Popular Applications & Methods
Key Application Key Application Key Application Key Application
Large Whole-Genome Sequencing (human, plant, animal)        
Small Whole-Genome Sequencing (microbe, virus)        
Exome Sequencing        
Targeted Gene Sequencing (amplicon, gene panel)        
Whole-Transcriptome Sequencing        
Gene Expression Profiling with mRNA-Seq        
miRNA & Small RNA Analysis        
DNA-Protein Interaction Analysis        
Methylation Sequencing        
Shotgun Metagenomics        
Optimized NGS Sample Tracking and Workflows

See how BaseSpace Clarity LIMS (Laboratory Information Management System) enabled this large genomics lab to standardize lab procedures and cope with increasing sample volumes from diverse clients.

Read Case Study
Run Time 12–30 hours < 1–3.5 days (HiSeq 3000/HiSeq 4000)
7 hours–6 days (HiSeq 2500)
< 3 days 19–40 hours
Maximum Output 120 Gb 1500 Gb 1800 Gb 6000 Gb§
Maximum Reads Per Run 400 million 5 billion 6 billion 20 billion|
Maximum Read Length 2 × 150 bp 2 × 150 bp 2 × 150 bp 2 × 150 bp
  Compare NextSeq Request Pricing Compare HiSeq Request Pricing Explore HiSeq X Request Pricing Compare NovaSeq Request Pricing

* For MiSeq V3 kits only.
† Specifications shown for an individual HiSeq X Sequencing System. HiSeq X is only available as part of the HiSeq X Five or HiSeq X Ten.
‡ Run time based on dual S2 flow cells run on a NovaSeq 6000 System. Run times on the NovaSeq 5000 System may be slightly longer.
§ Maximum Output is based on a dual flow cell run of S4 flow cells which have not been released; therefore, performance metrics are subject to change.
| Maximum Reads Per Run is based on a dual flow cell run of S4 flow cells which have not been released; therefore, performance metrics are subject to change.

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Find the System That’s Right for Your Application Needs

Compare our sequencing platforms and identify the best system for your lab and applications.

Compare NGS Platforms

See all product selection and experiment planning tools

Illumina has pioneered major advances for sequencing platform simplicity, flexibility, and performance. Sequencing output has grown over a thousand-fold, from less than 1 gigabase to 6 terabases per run, while the number of reads has increased from millions to billions. Experiments that once required complex workflows now use simple push-button sequencing.

Learn More About NGS
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NGS Platforms with Proven Performance

Illumina NGS instruments have been adopted by leading institutions around the globe, both big and small, and are the production platform for all major genome centers. More than 90% of the world’s sequencing data is generated using Illumina instruments.*

Each sequencing platform delivers exceptional data quality and performance, with flexible throughput and simple, streamlined workflows—for every kind of researcher, for every scale of study.

*Data calculations on file, Illumina, Inc. 2015.

How to Choose a Sequencing System

Determine the best benchtop sequencer or production-scale NGS platform to transform your lab. Ask the right questions to evaluate your needs.

  • What applications will you use most frequently?
  • Which instrumentation options best enable these applications?
  • What are the ongoing costs beyond the initial instrument purchase?

For further guidance about key factors to consider when making your decision, download the NGS System Buyer’s Guide.

Download Buyer's Guide