With the Infinium MethylationEPIC BeadChip Kit, researchers can interrogate over 850,000 methylation sites quantitatively across the genome at single-nucleotide resolution. Multiple samples, including FFPE, can be analyzed in parallel to deliver high-throughput power while minimizing the cost per sample.
Infinium HD array technology enables content selection independent of bias-associated limitations often associated with methylated DNA capture methods. The result is a pan-enhancer and coding region view of the methylome that can be used for epigenome-wide association studies on a variety of human tissues.
This kit includes content categories requested by methylation experts, such as:
MethylationEPIC data analysis is supported by the GenomeStudio Methylation Module. GenomeStudio Software enables researchers to effortlessly perform differential methylation analysis for small-scale studies. It features advanced visualization tools that enable researchers to view vast amounts of data in a single graph, such as heat maps, scatter plots, and line plots.
These tools and the GenomeStudio Genome Browser display valuable information such as chromosomal coordinates, percent GC, location in a CpG Island, and methylation β values.
For large-scale studies, there are many free analysis packages that work in the software framework R for normalization, and differential analysis of methylation data. Instructional videos explain the use of these data analysis packages.
Disease classifiers based on DNA methylation patterns offer the potential to predict clinical outcomes.
Read MoreMethylation arrays add another dimension to the study of COVID-19 and other infectious diseases.
Read MoreInfinium Methylation BeadChip Application Note
Application Note | PDF < 1 MB
Application Note | PDF < 1 MB
Technical Note | PDF 1 MB
Analyzing FFPE Samples with Infinium Microarrays
Technical Note | PDF < 1 MB
Technical Note | PDF < 1 MB
STM Reagent Improves Robustness of Infinium Methylation Assay
Technical Note | PDF < 1 MB
Infinium MethylationEPIC BeadChip Data Sheet | Illumina
Data Sheet | HTML
Automated bisulfite conversion for Infinium™ Methylation BeadChips
Technical Note | PDF 2 MB
Infinium HD Methylation Assay Manual Workflow Checklist Documentation
Infinium HD Methylation Assay Reference Guide Documentation
Infinium LiHa and Infinium RoMa Operating Manual Documentation
Infinium MethylationEPIC Kit Support Documentation
Infinium HD Assay for Methylation Lab Tracking Form Documentation
BeadArray Controls Reporter Software Guide Documentation
Infinium Assay Lab Setup and Best Practices Documentation
Infinium Assay Consumables and Equipment List Documentation
Infinium HD Methylation Assay Auto Workflow Checklist Documentation
Custom Protocol Selector
Generates customized, end-to-end instructions
The Infinium MethylationEPIC Kit is the recommended replacement product for the HumanMethylation450 BeadChip Kit, which has been discontinued. Illumina remains committed to providing you with high-quality support and service.