Microbes living in the host can influence cancer progression and treatment efficacy. Diet and drugs can disrupt microbiome diversity, and key species in the microbiome can cause local or systemic influences on host immunity.1,2
There is hope that future treatments may combine existing cancer therapies with methods to encourage growth of beneficial microbes or eliminate harmful ones. As NGS-based research continues to explore host-microbiome interactions, Illumina strives to evolve genomic technologies that complement and enable the promise of this field.
NGS methods have revolutionized the study of the microbiome.3 Without the need to culture or clone individual organisms, NGS enables simultaneous analysis of thousands of species within a microbial community. With the development of bioinformatic tools to manage large volumes of new information, this shift from single organism analysis enables accurate assessment of species diversity and measurement of dynamic fluctuations in microbial communities.
Researchers at Microba are investigating the genomes of microbes to improve our understanding of human health, disease, and microbial evolution.Read Interview
With high throughput and high sensitivity, NGS enables the identification of thousands of microbial species in a single sample.
Click on the below to view products for each workflow step.
Prepare sequencing ready libraries of bacteria, viruses, and other microbes to analyze transcriptome and metatranscriptome information.Illumina Stranded Total RNA Prep with Ribo-Zero Plus
Streamlined, cost-efficient, and scalable solution for total RNA analysis.
A fast, integrated workflow for a wide range of applications, from human whole-genome sequencing to amplicons, plasmids, and microbial species.
Speed, accuracy and simplicity for far reaching applications in microbiology.NextSeq 550 System
Flexible desktop sequencer for transcriptome and whole-genome sequencing.
Power for high-throughput microbial transcriptomics and flexibility to scale based on your project or workflow needs.NovaSeq 6000 System
High throughput and low cost for production-scale genomics.
Performs taxonomic classification of 16S rRNA targeted amplicon reads using an Illumina-curated version of the GreenGenes taxonomic database.DRAGEN Metagenomics Pipeline
Performs taxonomic classification of reads and provides single sample and aggregate reporting.
Data management and simplified bioinformatics for labs getting started and for rapidly scaling up sequencing operations.
Unify single-cell gene expression and ATAC-Seq to help reveal cellular mechanisms driving gene regulation.Read Tech Note
Learn how to incorporate protein detection into bulk RNA-Seq and develop a workflow for BEN-Seq, providing a holistic approach to cell analysis.Read App Note