Immuno-oncology is an emerging field that has taken great strides in the fight against cancer, bolstered by a refined understanding of how tumors evade the natural immune response. Leading immuno-oncology researchers are leveraging next-generation sequencing to discover biomarkers and apply genomics to personalized immunotherapy.
Research into the mechanisms tumors use to evade the immune response have led to promising therapeutic targets. These therapies boost the ability of the immune system to target cancer, or limit the tumor’s ability to evade the natural immune response.
Since the late 1800s, the field of immuno-oncology has been exploring the immune system and the development, progression, and treatment of cancer. With over a century's worth of discoveries as the guide, the past decade has seen an explosion in the translation of this research into new treatment modalities, often with unprecedented success.View Video
Studies have shown that response to certain therapies depends on numerous factors. NGS can be used in several ways to monitor these dynamic interactions, in real-time and with high analytical sensitivity.
Various factors in the microenvironment can influence the ability of the immune system to expand and infiltrate tumors.
Efficient assessment of mutations and understanding their correlation to immune response may help to develop new therapeutic methods.
An emerging body of evidence indicates that microbes in the gut can influence the ability of the immune system to fight cancer.
Illumina technology has facilitated discovery in the immuno-oncology field through various genomic applications. Read published research findings.
Illumina offers several library preparation and sequencing options with access to data analysis options for Immuno-Oncology Research. Streamlined workflows and flexible kit configurations accommodate multiple study designs.
Approximately 90% of the world’s sequencing data are generated using Illumina sequencing by synthesis (SBS) chemistry.*
Click on the below to view products for each workflow step.
The TruSeq RNA Access library prep kit provides a low-cost solution for analyzing human RNA isolated from limited or low-quality samples, including FFPE.TruSeq Exome
TruSeq Exome Library Prep Kit is a cost-effective library preparation and exome enrichment solution.
Flexibility and unprecedented throughput for virtually any genome, sequencing method, and scale of project.HiSeq 3000/HiSeq 4000 Systems
Patterned flow cell technology results in high throughput, low price per sample, and enhanced speed and performance.
*Data calculations on file. Illumina, Inc., 2015