Traditionally, cell biology research seeks to understand the contribution/function of a single gene, gene family, or signaling pathway to a complex disease. Researchers use signal-based methods such as microscopy, flow cytometry, protein blotting, and others. Given the multifactorial nature of complex diseases, this approach can be time-consuming and does not always result in conclusive findings.
Array and NGS technologies from Illumina can broaden cellular research beyond the conventional methods of protein interactions and single-gene functional studies. Illumina technology enables analysis across the genome, transcriptome, and epigenome. NGS results can inform experimental design and subsequent studies, ultimately saving time and allowing researchers to publish sooner.