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Ultra–high–resolution HLA typing

HLA Sequencing

Sequencing the HLA region can provide critical insight into immune disorders. Achieving high-resolution human leukocyte antigen (HLA) typing results with conventional methods requires multiple assays, systems, and analysis programs. HLA typing by next-generation sequencing (NGS) generates unambiguous, phase-resolved HLA typing results using a single assay, system, and analysis program.

A New Paradigm in HLA Sequencing
A New Paradigm in HLA Sequencing

The TruSight HLA Sequencing Panel delivers unprecedented accuracy, efficiency, and certainty in HLA typing—all in one assay. Together we are transforming possibility into progress: with our tools to accelerate genetic research and your commitment to improve human health.

HLA NGS Continuing Education

Join the Illumina HLA team in an engaging 3-day, hands-on training workshop to explore how NGS is delivering accuracy and efficiency to HLA typing. Attendees are eligible to receive ABHI continuing education credit (CEC).

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HLA NGS Continuing Education

The TruSight HLA Sequencing Panel v2 produces high-resolution typing of 11 HLA loci. Our comprehensive sample-to-report solution for HLA typing includes reagents and software optimized for HLA analysis. A simplified workflow enables turnaround time of less than 48 hours and increased efficiency with less than 4.5 hours of hands-on time.

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Sequencing HLA genes has been notoriously difficult due to high levels of sequence homology, dense variability, and poor characterization of the thousands of HLA alleles in the population. Highly accurate and robust Illumina sequencing by synthesis (SBS) chemistry is the most successful and widely adopted NGS technology worldwide.* Learn how this technology is becoming the platform of choice for HLA sequencing.

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Introducing TruSight HLA
Introducing TruSight HLA

The TruSight HLA sequencing solution offers streamlined, economical, and high-quality ultra-high–resolution HLA typing.

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Illumina Sequencing by Synthesis
Illumina Sequencing by Synthesis

Illumina SBS chemistry has revolutionized the study of genomics. See SBS chemistry in action.

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TruSight HLA v2 Data Sheet

Learn more about TruSight HLA v2 and see HLA typing results from Illumina sequencing of the IHWG cell lines.

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TruSight HLA v2 Whitepaper
TruSight HLA v2 Whitepaper

Results of repeated sequencing of 72 IHWG reference samples.

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