Science and Education

NET-Seq

UMI-4C

This variation on the 4C approach uses UMIs to derive high-complexity quantitative chromosome contact profiles with controlled signal-to-noise ratios. It is an efficient and accurate method for analyzing targeted loci. The method is paired with software to analyze the data (https://bitbucket.org/tanaylab/umi4cpackage).

Pros:
  • Improved sensitivity and specificity
  • Multiplexing allows robust comparison of contact distributions between loci and conditions
Cons:
  • None reported
  1. Schwartzman O., Mukamel Z., Oded-Elkayam N., et al. UMI-4C for quantitative and targeted chromosomal contact profiling. Nat Methods. 2016;13:685-691
For Research Use Only

Not for use in diagnostic procedures (except as specifically noted).

Innovative technologies

At Illumina, our goal is to apply innovative technologies to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. It is mission critical for us to deliver innovative, flexible, and scalable solutions to meet the needs of our customers. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and providing the highest level of quality, we strive to meet this challenge. Illumina innovative sequencing and array technologies are fueling groundbreaking advancements in life science research, translational and consumer genomics, and molecular diagnostics.

All trademarks are the property of Illumina, Inc. or their respective owners.
For specific trademark information, see www.illumina.com/company/legal.html.

© 2025 Illumina, Inc. All rights reserved.