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Illumina technology can advance immunology research by helping elucidate immune cell function and signaling. Immune cells work to protect the body from foreign invaders including viruses, bacteria, and parasites. Mutations and environmental factors can cause the immune system to malfunction and attack the body it is meant to protect. Many immune disorders are classified as complex diseases since they are influenced by both genetics and the environment.
Complex autoimmune disorders include lupus, rheumatoid arthritis, inflammatory bowel disease, and others. The cause and progression of many of these diseases are still not understood.
Array and next-generation sequencing (NGS) solutions from Illumina can provide immunology researchers with detailed insight into the potential genetic causes and functional consequences of variation.
TruSight HLA: Sequence 11 HLA loci for high-resolution, phase-resolved haplotyping in one assay.
Infinium ImmunoArray-24 v2 BeadChip Kit: Perform research to evaluate autoimmune disorder and immune function–associated genetic variants on a single array.
View publication summaries showing how researchers use NGS to map the human immune response at high resolution.
NGS can help researchers identify mutations that enable tumors to evade the immune response, as well as neoantigens that can boost T cell-mediated immunity.
Learn More About Immuno-Oncology Research
Dr Carl Anderson discusses integrated genomic research approaches in inflammatory bowel disease (IBD) research.
Gain a better understanding of genomic techniques used to profile the transcriptome and epigenome in complex, multifactorial disease.
Gain insight into human macrophages’ global reprogramming on the transcriptional level.
See how researchers use NGS to study T cell receptor diversity and autoimmune diseases, and unravel other disease mechanisms.
Read publication reviews showing the utility of NGS for immunology-related cancer research.
Researchers query the genome with NGS and high-throughput genotyping to identify novel risk loci for immune-mediated disease.
New epigenetics method maps open chromatin regions to give a multidimensional portrait of gene regulation in complex disease.
Jan Veldink, PhD shares how integrative genomics helped drive his ALS research, leading to the discovery that NEK1 is an ALS gene.
A reproducible, economical method for sequencing coding RNA, including FFPE samples. View Kit.
See All RNA-Seq SolutionsFlexible desktop sequencing systems that support various applications, from targeted panels to whole-genome sequencing. Learn More.
See All SequencersThe Illumina genomics computing environment for NGS data analysis and management, so labs can analyze, archive, and share data easily. Learn More.
See All Data Analysis Tools