Uncovering the underlying factors that contribute to host susceptibility and immune response is essential to unravel the complexities of COVID-19. It is crucial to understand how genetic variance contributes to susceptibility as well as define how the immune system responds during the course of the disease. Illumina genomics solutions allow researchers to interrogate host genetic variance and profile the molecular mechanisms that drive immune responses.
The key benefits of using Illumina technology for studying the immune response to COVID-19 include:
|Host genetics research||
|Host immune response profiling||
|Microbiome & host response||
Dr. Lee Murphy’s core lab at the University of Edinburgh applies a genomic approach to study host genetic variability in disease progression and outcome in SARS-CoV-2 hospitalized patients. The team and collaborators perform genotyping and WGS on DNA samples, as well as mRNA-Seq on the NextSeq 2000 System.View Video
The study of microbial communities found in and on the human body allows researchers to understand the role of microbes in health and disease.
A DNA sequencing method that enables comprehensive sampling of all genes in all organisms in a given complex microbial sample.
Complex diseases result from a combination of genetic and environmental factors. Array and sequencing technologies can help reveal the underpinnings of these diseases.
Expand cell and molecular biology research beyond conventional methods with next-generation sequencing.
With single-cell RNA-Seq, researchers can study cellular differences that are often masked by bulk sampling.