Investigating candidate genes associated with neurodegenerative diseases

Neurodegeneration Panel Consortium Product

The TruSeq Neurodegeneration Panel is a targeted sequencing panel that leverages expertise from leading researchers in the neurogenomics community. It was designed with input from scientists studying neurodegenerative diseases.

The content of the panel was carefully selected based on recent scientific findings. It features over 8.7 Mb of content, including introns, exons, untranslated regions, and promoters to support surveys of both coding and noncoding gene regions. The panel uses tagmentation technology for rapid library prep, and is part of a convenient workflow that includes sequencing and intuitive data analysis.

Enabling Discovery of Rare Risk Variants

The TruSeq Neurodegeneration Panel aims to help researchers identify genetic variants that may shed light on neuropathological onset and progression.

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The TruSeq Neurodegeneration Panel is now available as a consortium product.
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Experts in neurodegenerative disease research carefully selected content for the TruSeq Neurodegeneration Panel based on recent scientific findings. The panel includes both risk-validated genes and genes implicated to be associated with the following neurodegenerative diseases:

  • Alzheimer's disease
  • Parkinson's disease
  • Amyotrophic lateral sclerosis
  • Frontotemporal dementia
  • Dementia with lewy bodies
  • Dystonia
  • Early-onset dementia
Genetic Insight into Neurodegenerative Disorders

Recognizing a need for this research tool, Alan Pittman, PhD and others helped Illumina design the TruSeq Neurodegeneration Panel.

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