Infinium Asian Screening Array-24 v1.0 BeadChip
A powerful, cost-effective genotyping array for large-scale genetic studies and pharmacogenomics in East Asian populations.
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Product Highlights
The Infinium Asian Screening Array (ASA) combines genome-wide coverage of East Asian populations, relevant clinical research content, and scalability to deliver a powerful, cost-effective tool for genomic screening.
East Asian Genomic Coverage
The array was built using an East Asian reference panel containing 9000 whole-genome sequences. It includes coverage of populations underrepresented in the 1000 Genomes Project.
Widespread Adoption
The Infinium Asian Screening Array builds on the success of the Infinium Global Screening Array, which was developed by a community of researchers, healthcare networks, direct to consumer companies, and service providers. Illumina screening arrays have been widely adopted, with over 20 million samples ordered by a global community of users.
Clinical Research and Disease-Related Content
The array provides a genomic tool for disease risk profiling, pharmacogenomics research, wellness and lifestyle reporting, and complex disease research. It includes updated markers from clinical databases, including ClinVar and PharmGKB.
Predesigned booster content is available as an add-on to the array.
Robust, Trusted Assay and Highly Scalable Workflow
The array supports genotyping and CNV calling for several sample types, including saliva, blood, buccal swabs, and formalin-fixed, paraffin-embedded (FFPE) samples. The Infinium platform is trusted for excellent data quality, with call rates > 99% and reproducibility > 99.9%. The high-throughput Infinium workflow maximizes sample processing while minimizing costs, instrumentation, lab space, and hands-on time.
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Specifications
Product Comparison
| Infinium Asian Screening Array-24 v1.0 BeadChip | Infinium Global Screening Array-24 Kit | Infinium Global Diversity Array-8 Kit | |
|---|---|---|---|
| Description | A powerful, cost-effective genotyping array for risk screening, pharmacogenomics, and large-scale genetic studies in East Asian populations. | An economical next-generation genotyping array that enables population-scale genetics, translational research, variant screening studies, and precision medicine research by combining highly optimized multiethnic genome-wide content, curated clinical research variants, and QC markers. | The 8-sample Infinium Diversity Array provides targeted coverage of more than 4800 key genes across the genome. Approximately 1.8M markers are included on the BeadChip for high exonic coverage in regions of disease relevance, providing highly accurate copy number variation calls, and an average resolution of 1.5Mb. |
| Input Quantity | 200 ng DNA | 200 ng DNA | |
| Method | Genome-Wide Genotyping Array, High-Throughput Genotyping Array | Genome-Wide Genotyping Array, High-Throughput Genotyping Array | Genome-Wide Genotyping Array |
| Number of Markers | Fixed markers: ~ 660,000, Custom marker add-on capacity up to 50,000 | Fixed markers: ~ 654,027 Custom marker add-on capacity: Up to 100,000 |
|
| Number of Samples | 24 samples per array | 24 samples per array | |
| Sample Throughput | ~2304 samples per week (estimate for 1 iScan System, 1 AutoLoader, 2 Infinium Automated Pipetting Systems, and a 5-day work week) | ~5760 samples/week max per iScan (throughput and scan times may vary based on laboratory and system configurations.) | |
| Species Category | Human | Human | Human |
| System Compatibility | iScan | iScan | iScan |
| Technology | Microarray | Microarray | Microarray |
Customer Stories
Bringing Meaning to Genetic Information
MyDNA recently began partnering with Illumina customers using the Global Screening Array and Asian Screening Array in their genetic test offerings.
Read InterviewScalable High-Throughput Array Enables Ethnic Chinese Genome Database Development
Fast Infinium array analysis and broad genome coverage support personal genetic testing services and database development.
Read InterviewAsian Screening Array - Whole-Genome Sequences
| Population | Abbreviation | Cohort | Sequence Depth |
|---|---|---|---|
| Chinese | CHS-GIS | Genomics Institute of Singapore | 30× |
| Southern Han Chinese | CHS | 1000G - Southern Han Chinese | 2–4× |
| Chinese Dai | CDX | 1000G - Chinese Dai in Xishuangbanna | 2–4× |
| Han Chinese | CBD | 1000G - Bejing | 2–4× |
| Japanese | R-JAP1 | RIKEN W13 | 15× |
| Japanese | R-JAP2 | RIKEN W1–6 | 30× |
| Japanese | R-JAP3 | RIKEN W18 | 30× |
| Japanese | K-JAP | KYOTO | 3–15× |
| Japanese | JAP | 1000G - Tokyo | 2–4× |
| Korean | M-KOR | MACROGEN | 15–30× |
| Korean | KPGP | The Personal Genome Project Korea (KPGP) | ~35× |
| Malaysian | MAL | Singapore Population Health Study | 30× |
| Mongolian | MON | MACROGEN | 30× |
| Vietnamese | KVT | 1000G - Kinh in Ho Chi Minh | 2–4× |
Description of whole-genome sequences used to develop the Asian Screening Array v1.0
Clinical research content on the Infinium Asian Screening Array-24 v1.0 BeadChip
Content was expertly selected from scientifically recognized databases to create a highly informative array for clinical research applications.
Broad spectrum of pharmacogenomics markers
Clinical research content features an extensive list of pharmacogenomics markers selected based on CPIC guidelines and the PharmGKB database. Markers are arranged according to level of evidence as defined by the PharmGKB database. VIP: very important pharmacogene.
Product Literature
Infinium™ Chinese Genotyping Array-24 v1.0 BeadChip
Data Sheet | PDF < 1 MB
Infinium Asian Screening Array-24 v1.0 BeadChip
Data Sheet | PDF < 1 MB
Manuals and Support Information
Infinium Asian Screening Array Documentation
Custom Protocol Selector
Generates customized, end-to-end instructions
Infinium Global Screening Array-24 Kit
This next-generation genotyping array provides a scalable, cost-effective solution for population genetics, pharmacogenomics studies, and precision medicine research.
Infinium Global Diversity Array-8 Kit
The Global Diversity Array-8 (GDA) BeadChip combines exceptional coverage of clinical research variants with optimized multi-ethnic, genome-wide content.
Infinium Omni2.5-8 Kit
This 8-sample BeadChip array features ~2.4 million markers, and delivers exceptional genomic coverage rates across diverse populations.