The SureMDA DNA Amplification System uses a simple and reliable method to achieve uniform genome amplification from single cell or limited samples. Following SureMDA amplification, samples are processed and hybridized to the HumanKaryomap-12 BeadChip array.
- Dedicated buffers and reagents deliver high yields of DNA from a single or a few cells of an embryo biopsy
- Uses gentle alkaline incubation to maximize DNA fragment length so that genomic loci and sequences are uniformly represented
Karyomapping is a comprehensive preimplantation genetic diagnosis (PGD) method. It uses genome-wide linkage-based analysis to identify the inheritance of single-gene defects from a single cell, or a small number of cells, isolated from an embryo. The first step in karyomapping is to amplify total DNA isolated from the cell.