Leverage automated library preparation on the fireflyGO liquid handler for rapid, streamlined NGS workflows with fewer touchpoints and reduced errors.
Enable cost-efficient, accurate library preparation for targeted oncology research applications with Pillar Biosciences oncoReveal panels using SLIMamp technology.
Achieve fast run times on the MiSeq i100 Series with breakthrough simplicity, paired with DRAGEN and Illumina Connected Insights for streamlined analysis.
Reduce workflow complexity and staffing constraints with the fireflyGO automated liquid handler.
Using automation can reduce hands-on time and minimize human error across your targeted oncology NGS workflow compared to manual approaches. With Pillar Biosciences oncoReveal panels on the fireflyGO automated liquid handler, you can perform next-generation sequencing (NGS) using the MiSeq i100 Series with DRAGEN and Illumina Connected Insights for analysis, all in a streamlined, end-to-end research solution.
Increased throughput
Reduced hands-on time
Fewer errors
Easy setup
Intuitive interface
Small footprint
Cloud deployment of new protocols
Prepare, sequence, and analyze with a streamlined and standardized automated liquid handling system purpose-built for NGS-based targeted oncology research.
Automated library preparation with an intuitive interface and a small footprint.
fireflyGO automated liquid handler
Reduce workflow complexity with easy setup and efficient automation.
Enable cost-efficient, accurate library preparation using select Pillar oncoReveal panels powered by SLIMamp technology.
Rapid run times for oncology research.
Perform fast, simple sequencing on your benchtop.
Secondary and tertiary analysis with a simplified user interface.
Software application optimized for select oncoReveal panels.
For interpretation of SNVs, indels, CNVs, RNA fusions, and research reporting.
| fireflyGO specifications | |
| Throughput | 24-, 16-, 8-, or 1-samples |
|---|---|
| Capacity | Up to 16 SBS labware positions on two independently moving decks |
| Integrated modules | Gripper, active heating/cooling system, Inheco On-Deck Thermal Cycler 96 |
| User interface | LCD touchscreen with guided instrument setup and protocol execution; transferable cloud-based methods |
| Safety | Fully enclosed with user protection systems |
Learn more about Illumina oncology research solutions that help laboratories generate high‑quality, reproducible genomic insights with intuitive and scalable workflows.
Explore the trusted portfolio of sequencers and microarray scanners from Illumina designed to support a wide range of applications.
Reduce hands-on time and minimize errors with high- and low-throughput walk-away automation protocols.
The fireflyGO automated liquid handler is optimized for the MiSeq i100 Series to deliver the fastest workflow and it is also compatible with the higher throughput NextSeq 1000 and NextSeq 2000 Sequencing Systems.
The fireflyGO automated liquid handler is intended to work with Pillar oncoReveal Panels from Illumina. Current compatible panels include Pillar oncoReveal Myeloid Panel, Pillar oncoReveal Core LBx Panel, Pillar oncoReveal Multi-Cancer CNV and RNA Fusion Panel. Additional Pillar oncoReveal panels will be available by the end of 2026.
The fireflyGO automated liquid handler increases laboratory throughput by enabling faster, more consistent processing of samples. By reducing manual steps and allowing workflows to run more efficiently, laboratories can scale sample volumes without proportionally increasing staffing or labor hours. The fireflyGO is able to handle up to 24 samples per run in 5–6.5 hours depending on the panel and sample type.
Laboratories should consider automated liquid handling when they need to improve reproducibility, reduce hands-on time, increase throughput, or support growing sample volumes. Automation is especially valuable for workflows that involve repetitive or time‑consuming liquid handling steps.
Yes. Illumina offers additional automation options and works with partners to support automated workflows across sequencing, library preparation, protein preparation, and microarray applications. These solutions help laboratories design automation strategies that align with specific needs. Learn more about automated library preparation.
Talk to an expert to learn more about the fireflyGO automated liquid handler.
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