Leveraging the speed and affordability of complementary metal-oxide-semiconductor (CMOS) technology and the accuracy of sequencing by synthesis (SBS) chemistry, the iSeq 100 System enables virtually any lab to acquire powerful next-generation sequencing (NGS) technology.
By providing both higher data resolution and deeper coverage compared to qPCR and Sanger sequencing, the iSeq 100 System allows greater statistical confidence for calling variants or low-frequency alleles. Complement existing methods or introduce NGS for the first time with the iSeq 100 System.
The iSeq 100 System provides incremental sequencing capacity to meet the needs of current workflows, while maintaining trusted Illumina data quality. Use the iSeq 100 System to conduct smaller projects, avoid running small sample batches on high-throughput instruments, evaluate libraries before a large-scale run, or perform a proof-of-principle study.
The iSeq 100 System offers flexibility to transition easily between multiple DNA and RNA sequencing applications, including small genome sequencing, targeted gene sequencing, and gene expression profiling. It is also compatible with the fastest library preparation workflows available.
Find an introduction to NGS technology and how it works, a buyer’s guide, and other educational resources to help you get acquainted with the technology.Learn More
Learn how to get started with the iSeq 100 System with step-by-step guides and training videos. See how easy it can be to bring NGS to your lab.Get Started
We’ve taken most of the manual work out of the NGS data analysis process. Local Run Manager software is installed on every iSeq 100 System and automatically performs on-instrument data analysis. The software has a user-friendly touch-screen interface for starting a sequencing run, monitoring run status, viewing results, and analyzing data.Learn More
The iSeq 100 System is a lightweight, easy-to-use instrument, making self-installation simple. Illumina scientists and engineers are available to provide additional support and answer questions, with installation and qualification services to help you get started. During maintenance events, we’ll provide a temporary replacement for your iSeq 100 System, so you can continue running experiments without interruption. We also offer training courses, either at your own lab or online, to help bring laboratory personnel quickly up to speed.