Profile entire microbial communities in complex environmental samples

Environmental Metagenomics

Environmental metagenomics is the study of organisms in a microbial community based on analyzing the DNA within an environmental sample.

Examples include profiling microbial populations in water samples taken from deep ocean vents or in soil samples from human-made environments like active mineral mines. Environmental metagenomics study data are used for agricultural microbiome analysis, ecological remediation, or other biological investigations.

Environmental Metagenomics

Environmental metagenomics as a field was extremely limited prior to the advent of next-generation sequencing (NGS). NGS provides researchers the capability to profile entire microbial communities from complex samples, discover new organisms, and explore the dynamic nature of microbial populations under changing conditions.

Common NGS methods for environmental metagenomics studies include:

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In Hot Water with Extremophiles

Dr Brian Hedlund uses genomics to study the microbes that populate hot springs. He is discovering new classes of organisms, learning how to culture microbes that would not have been culturable without genomic information, and learning new insights about microbial life.

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In Hot Water with Extremophiles

Environmental Metagenomics Research Stories

Driving Insights Through Microbiome Profiling
Driving Insights Through Microbiome Profiling

This metagenomic shotgun sequencing workflow enables accurate DNA detection from soil.

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eDNA Offers a Powerful Look at Biodiversity
eDNA Offers a Powerful Look at Biodiversity

NGS and environmental DNA (eDNA) metabarcoding enable researchers to monitor a variety of ecosystems accurately.

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Sailing the Seven Seas for an Epic Plankton Studyy
Sailing the Seven Seas for an Epic Plankton Study

An epic ocean expedition sequenced salt water samples from around the globe to survey plankton diversity in marine ecosystems.

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Environmental DNA sequencing is a rapidly emerging method for studying biodiversity and monitoring ecosystem changes. For some sample types, using a combination of environmental DNA sequencing approaches can help uncover the full breadth of diversity in an ecological sample, including both bacterial and eukaryotic species.

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Researching microbial symbiosis
Researching Microbial Symbiosis

University of Wisconsin-Madison researchers explore a microbe-cycling hypothesis with tree sloths and paired-end 16S amplicon sequencing.

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Lessons from the H3MP Project

Listen to Dr. Jack Gilbert discuss microbiology implications for home, hospital, and human (H3) interactions.

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Metagenomic Analysis of Environmental Samples

Shotgun metagenomic sequencing with the NextSeq 500 System provides insight into microbial responses to environmental changes in a water reservoir.

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Metagenomics of Wine and Cheese Facilities
Metagenomics of Wine and Cheese Facilities

Researchers use NGS to identify and understand the constellation of microbes that deliver flavor to cheese and wine.

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