Hardware and accessories required to run the Infinium XT assay are conveniently bundled into starter and automation kits. Additional hardware and software is available to optimize workflow and maximize sample throughput.
Required components to run the Infinium XT Assay:
Infinium XT Starter Kit: hardware and accessories to run the Infinium XT assay
Infinium XT 96-Tip Guide: tip guides used for hybridization step
iScan System 110/220V: scanner and accessories for BeadChip imaging
Optional hardware to maximize sample throughput and streamline processing of the Infinium XT Assay:
AutoLoader (Single or Dual): robot and accessories to automate iScan System loading
Illumina LIMS: Complete Illumina Laboratory Information Management System (LIMS) to support Infinium processing
Infinium Genotyping Automation Post-Amplification: Robotic system for automated processing
96-Tip Liquid-Handling Robot: Robotic system for automated processing (future update).
This solution enables large-scale genetic improvement programs in agrigenomics and supports large-scale screening for biobanks and personalized medicine initiatives. It uses a high-efficiency, flexible workflow.
Production Scale: Optimized assay and 96-sample BeadChip enables processing of 100,000 to upwards of 1,000,000 samples/year per lab
Flexible Content: Targeted single or multispecies assays of 100s to 50,000 SNPs with at least 95% conversion rate guaranteed for custom panels
High Efficiency Workflow: Total assay turnaround time reduced from 3 days to 2 days with less hands-on time
Infinium XT simplifies the custom assay design process, reduces overall hands-on time, and enhances automation robot performance and utilization. The workflow offers an option to reduce the overall turnaround time, if the time to answer is more important than maximum weekly output.
Streamlined Sample Preparation and Data Analysis
A high-throughput solution like Infinium XT needs integrated systems that streamline sample preparation and analysis. The Illumina Automation Control software for the Tecan liquid handling robot has been updated to increase sample processing efficiency. An enhanced data analysis software solution offers real-time data generation and on-demand QC report functionality so production issues can be identified and corrected earlier in the process.
Updated software for GenomeStudio speeds up genotype cluster generation, reducing overall analysis turnaround time. Also, a genotyping module for agricultural and other applications involving polyploid species is now included.
After a cluster file is created, production-level analysis can be transitioned to Beeline Software. This software significantly reduces the time needed to observe quality performance specifications, generate genotyping reports, and analyze polyploid data, without removing the flexibility for manual intervention.