By retaining the precise location of biological molecules within a tissue, spatial methods can further our understanding of mechanisms in health and disease.
Next-generation sequencing offers the sensitivity and specificity that researchers need to detect low levels of circulating tumor DNA in the bloodstream.
Sequence thousands of organisms in parallel. Identify unculturable or low-abundance microbes, or evaluate microbial diversity.
Sequence the entire genome of a bacterium, virus, or other microbe.
Capture genomic regions of interest via hybridization to target-specific biotinylated probes.
Select and sequence specific transcripts of interest for gene expression profiling studies.
Enhance epigenetic studies with high-coverage density and flexibility enabled by sequencing-based DNA methylation analysis.
Chromatin immunoprecipitation sequencing (ChIP-Seq) is a powerful method for analyzing DNA-protein interactions and performing genome-wide surveys of gene regulation.
The assay for transposase-accessible chromatin with sequencing (ATAC-Seq) is a popular method for determining chromatin accessibility across the genome.
Ultra-deep sequencing of PCR amplicons enables cost-effective analysis of up to hundreds of target genomic regions in one assay.
Targeted gene sequencing panels are useful tools for analyzing specific mutations in a given sample.
Analyze coding plus multiple forms of noncoding RNA for a comprehensive picture of the transcriptome.
Sequencing the 16S ribosomal RNA (rRNA) gene is a culture-free method to identify and compare bacteria from complex microbiomes or environments that are difficult to study.
Identify unique receptor variants to map the vast repertoire of immune cells that are capable of recognizing a seemingly boundless array of targets.
*The NextSeq 1000 and NextSeq 2000 Systems are scalable platforms that can support a broad range of current and emerging applications beyond those listed here.
The P3 flow cell on the NextSeq 2000 is an excellent fit for multiomics studies. Use multiomics to better connect genotype to phenotype and obtain a full cellular readout not found through single multiomics approaches.
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These summaries of peer-reviewed publications highlight how Illumina technology is furthering research.
Ask virtually any question related to the genome, transcriptome, or epigenome of any organism. Explore a broad range of NGS methods.
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