Targeted arrays and sequencing solutions for focused genotyping studies

Targeted Genotyping

Targeted genotyping approaches provide a cost-effective alternative to whole-genome methods, when genome-wide genotyping is not practical or necessary. Targeted genotyping conserves lab resources and enables deeper coverage of rare variants. Illumina offers microarray and next-generation sequencing (NGS) genotyping solutions to target the exome or focus on specific genes of interest.

  • Allows researchers to focus time and expenses on specific regions of interest
  • Generates a smaller, more manageable data set, thereby reducing data analysis burdens
  • Offers a cost-effective solution with reduced turnaround time compared to broader approaches

Targeted arrays allow you to genotype specific sets of targeted single nucleotide polymorphisms (SNPs), and focus research efforts on biologically meaningful variants. Microarrays with targeted content also enable greater throughput for screening high sample volumes. Illumina offers a variety of disease-specific and population-specific array solutions for targeted genotyping.

Genotyping to Understand Psychiatric Disorders

Dr. Abraham Palmer uses targeted arrays and NGS to identify genes that influence behavior.

Read Interview
Array and Library Prep Kit Selector

Find and compare targeted human genotyping arrays with this simple tool.

Find the Right Array Find the Right Array
Custom Targeted Genotyping

Develop genotyping arrays with custom markers to target any genomic regions or variants of interest, for any species.

Explore Custom Genotyping

Genotyping by sequencing (GBS) offers efficiency for discovering, validating, and screening genetic variants using a highly targeted approach. Targeted GBS approaches can complement arrays by detecting novel variants in specific genome regions, and provide a lower cost alternative for some genotyping applications. Deep sequencing of targeted regions also helps characterize rare variants. Learn more about GBS.

Targeted Fish Genotyping with Sequencing

Scientists developed the Genotyping-in-Thousands by sequencing (GT-seq) method to genotype thousands of fish simultaneously.

Read Interview
Cancer Germline Mutation Analysis
Cancer Germline Mutation Analysis

Identify germline mutations that predispose individuals to cancer using targeted microarrays and next-generation sequencing. Learn more about cancer germline mutation studies.

Biobank Sample Genotyping
Biobank Sample Genotyping

Illumina helps to maximize biobank specimen value by illuminating the underlying genetics of your samples. Learn more about biobank analysis solutions.

Disease Variant Validation
Disease Variant Validation

After a variant is identified and associated with disease, targeted array and sequencing methods can help determine how a variant affects disease biology. Learn more about disease variant validation.

Genotyping Plants and Animals
Plant and Animal Genotyping

Uncovering genetic variation in animals and plants can help inform breeding decisions, and may reveal mutations responsible for disease or parasite susceptibility. Learn more about plant and animal genotyping.

Interested in receiving newsletters, case studies, and information on sequencing methods? Enter your email address.
Pharmacogenomics and Cardiovascular Disease
Pharmacogenomics and Cardiovascular Disease

Find out how researchers used an Illumina array to identify responder genotypes in a failed cholesterol drug trial.

Read Interview
Genomics Consortia
Genomics Consortia

Illumina helps researchers who share similar goals join efforts to pool resources and create genomics tools.

Learn More
Amplicon Sequencing
Amplicon Sequencing

Amplicon sequencing is a highly targeted approach that can be used to genotype large genomes.

Learn More
HLA Genetics in Autoimmune Disease
HLA Genetics in Autoimmune Disease

Researchers query the genome with NGS and high-throughput genotyping to identify novel risk loci for immune-mediated disease.

Read Interview
Recreating a Face Based on DNA
Recreating a Face Based on DNA

Researchers identify genetic variants that influence facial features to enable facial imaging from DNA.

Read Interview
Genetics of Developmental Language Disorders
Genetics of Developmental Language Disorders

Arrays and NGS methods fuel research uncovering genetic variants that affect language and reading disorders.

Read Article