VeriSeq PGS

A fully validated next-generation sequencing solution for PGS, providing accurate results in aneuploidy screening and extending future opportunities. Read More...
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VeriSeq™ PGS Kit - MiSeq®

RH-101-1001

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MiSeq® Reagent Kit v3 - PGS

RH-102-1001

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Product Highlights

The VeriSeq PGS Kit takes advantage of next-generation sequencing (NGS) technology to provide comprehensive, accurate screening of all 24 chromosomes for selection of embryos most likely to be euploid. Preimplantation genetic screening (PGS) results generated using VeriSeq PGS are comparable to those achieved with the widely used array-based 24sure technology. In addition, NGS offers the opportunity for improved assay workflow, higher throughput, and enhanced performance.1

  • Industry-leading data quality: More than 90% of the world’s sequencing data is generated by Illumina sequencing by synthesis (SBS) chemistry*
  • Fast, streamlined workflow: Sample to answer in approximately 12 hours
  • High-throughput analysis: Screen up to 24 samples per run
Ultra-Low Input

NGS offers a highly sensitive method for screening embryos, requiring as little as 1 ng of DNA from a SurePlex DNA amplification reaction. DNA can be obtained from a blastomere biopsy, from a day 3 embryo, or from a trophectodermal (TE) biopsy from a blastocyst.

*Data calculations on file. Illumina, Inc., 2015.

Specifications

Method-Specific Workflow Example

 

Customer Stories

Sometimes the Journey to Parenthood Needs a Technology Nudge

New technologies and procedures help tackle infertility.

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A Preimplantation Genetic Diagnosis Pioneer Takes a Look Back

Dr. Leeanda Wilton of Melbourne IVF codeveloped genomic methods that were key predecessors of technologies that are now contributing to successful IVF pregnancies.

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Supporting Data and Figures

 

Manuals and Support Information

VeriSeq PGS Library Prep Kit Support Documentation  

Custom Protocol Selector
The Custom Protocol Selector enables you to generate your own customized documentation, specifically tailored to your experiment.

All VeriSeq PGS Library Prep Kit Support 

Related Products

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24sure Microarray

Widely used microarray and proven method for accurate, timely preimplantation genetic screening results.


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SurePlex DNA Amplification System

Used to generate a DNA template from single cells. Ideal for use with 24sure aneuploidy screening arrays or VeriSeq PGS applications.


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MiSeq Reagent Kit v3

Optimized chemistry to increase cluster density and read length, and improve sequencing quality scores, compared to earlier MiSeq reagent kit versions.


References
  1. Fiorentino F, Bono S, Biricik A, et al. Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles. Hum Reprod. 2014;29(12):2802–2813.
  2. Yang Z, Liu J, Collins GS, Salem SA, et al. Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis patients: results from a randomised pilot study. Mol Cytogenet. 2012;5: 24.