The Infinium Omni2.5Exome-8 BeadChip array delivers comprehensive coverage of common, rare, and exonic SNP content from the 1000 Genomes Project (1kGP)1, providing maximum genomic information of diverse world populations. With combined markers from the Infinium Omni2.5-8 Kit and Infinium Exome-24 Kit, the Infinium Omni2.5Exome-8 BeadChip is a powerful tool for next-generation genotyping and genome-wide association studies (GWAS).
Using the proven iScan System and integrated analysis software, these eight-sample BeadChips offer high throughput, optimized tag SNPs, functional exonic content, and fully supported copy number variation (CNV) analysis. Combined with convenient packaging and a streamlined PCR-free protocol, the Infinium Omni2.5Exome-8 BeadChip Kits provide a optimized DNA analysis solution.
Learn More About Human Genotyping
View manifest (array content) filesInfinium Omni2.5Exome-8 Kit | Infinium Exome-24 Kit | Infinium CoreExome-24 Kit | Infinium OmniExpressExome-8 Kit | Infinium Omni5Exome-4 Kit | |
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Description | Combines >2.5 million tag SNPs from the HapMap and 1000 Genomes projects (>2.5%MAF) with >240,000 markers from the Infinium Exome-24 BeadChip array, to enable genome-wide variation studies while maximizing coverage of functional exonic SNPs. | Study putative functional exonic variants that consist of >240,000 markers representing European, African, Chinese, and Hispanic individuals, and a range of common conditions, from type 2 diabetes to cancer, psychiatric disorders, and more. | Includes all of the tag SNPs found on the Infinium Core-24 BeadChip, plus over 240,000 markers from the Infinium Exome-24 BeadChip, with the capacity to add up to 100,000 semi-custom markers for economical large-scale genotyping studies. | Offers over 274,000 functional exonic markers while delivering high coverage of putative functional exonic variants selected from over 12,000 individual exome and whole-genome sequences, for studying novel associations with traits and diseases. | A high-density array that provides coverage of common, intermediate, and rare SNPs using functional exonic content, for genome-wide genotyping and copy number variation studies. |
Number of Markers | Fixed markers: 2,618,000, Custom marker add-on capacity: None | Fixed markers: 244,883, Custom marker add-on capacity: Up to 400,000 (with + kit versions) | Fixed markers: 567,218, Custom marker add-on capacity: Up to 100,000 (with + kit versions) | Fixed markers: 958,497, Custom marker add-on capacity: Up to 30,000 | Fixed markers: 4,548,474, Custom marker add-on capacity: None |
Number of Samples | 8 samples per array | 24 samples per array | 24 samples per array | 8 samples per array | 4 samples per array |
Sample Throughput | ~1728 samples/week per iScan (max throughput and scan time may vary based on lab and system configurations) | ~2304 samples per week (estimate for 1 iScan System, 1 AutoLoader 2.x, 2 Infinium Automated Pipetting Systems, and a 5-day work week) | ~2304 samples per week (estimate for 1 iScan System, 1 AutoLoader 2.x, 2 Infinium Automated Pipetting Systems, and a 5-day work week) | ~960 samples per week (estimate for 2 iScan Systems, 1 AutoLoader 2.x, 2 Infinium Automated Pipetting Systems, and a 5-day work week) | ~544 samples per week (estimate for 2 iScan Systems, 1 AutoLoader 2.x, 3 Infinium Automated Pipetting Systems, and a 5-day work week) |
Species Category | Human | Human | Human | Human | Human |
Dr. Marie-Pierre Dube and researchers at the Montreal Heart Institute used the Infinium HumanOmni2.5Exome BeadChip to identify responder genotypes in a failed cholesterol drug (dalcetrapib) trial.
Learn MoreThe HUNT Biobank and Lifandis AS provide access to biological samples and corresponding clinical data from more than 250,000 individuals in the Norwegian population using Illumina off-the-shelf and custom Infinium HumanExome BeadChips.
Learn MoreInfinium Omni2.5Exome-8 v1.5 BeadChip
Data Sheet | PDF < 1 MB
Infinium LCG Assay Reference Guide Documentation
Infinium LCG Assay Manual Workflow Checklist Documentation
Infinium Assay Lab Setup and Best Practices Documentation
Infinium LCG Assay Automated Workflow Checklist Documentation
Infinium Omni2.5Exome-8 Kit Support Documentation
Infinium Assay Consumables and Equipment List Documentation
Infinium LCG Assay Lab Tracking Form (15023142) Documentation
The HumanOmni2.5Exome-8 BeadChip Kit has been renamed to Infinium Omni2.5Exome-8 Kit. Kits with either name on the label contain the same quality reagents and follow the same workflow.