TSO Comprehensive workflow—Batch up to seven patient samples and two control samples per run using TSO Comprehensive. The library preparation and enrichment steps take 2 days. The fully automated workflow on the NextSeq 550Dx System sequences samples; performs base calling and QC, variant calling, and interpretation; and generates a clinical report. The entire workflow is complete in 4-5 days.
Genes with key actionable biomarkers for multiple solid tumor types—Genes listed represent a subset of genes present in the TSO Comprehensive (EU) panel. Content analysis provided by Pierian based on IVD software Knowledge Base v8.5 (February 2023). ‡CNS, central nervous system. *Genes linked to current drug labels or guidelines. †Based on evidence in scientific literature, presence in clinical trials, or linked to labels in other histologies.
Clinical report for TSO Comprehensive—Reported variants are categorized as clinically significant or potentially clinically significant based on an expertly curated knowledge base that includes clinical guidelines, drug labels, clinical trials, and peer-reviewed literature. The easy-to-read output is intended to increase confidence in treatment decisions.