A new version of the Infinium CoreExome-24 BeadChip, v1.4, is available. The content does not vary significantly from the v1.3 BeadChip, with only a few minor SNP changes (see details).
The customizable Infinium CoreExome-24 BeadChip offers an economical way to perform and support large genetic studies, especially large-scale genotyping studies. This array can also be used to quickly and easily obtain baseline sample data sets for a variety of downstream applications, including common variant, sex confirmation, mitochondrial DNA, ancestry, loss-of-variant, indel, and copy number variation (CNV) studies.
Developed in collaboration with several leading research institutions, the Infinium CoreExome-24 BeadChip includes all the tag SNPs found on the Infinium Core-24 BeadChip, plus over 240,000 markers from the Infinium Exome-24 BeadChip. For greater flexibility, the Infinium CoreExome-24+ version of the BeadChip can be customized to include up to 100,000 additional markers.
The Infinium CoreExome-24 BeadChips use the Infinium high-throughput screening (HTS) 24-sample format, enabling high content flexibility, throughput capacity, and genotyping accuracy. When combined with the proven iScan System, these BeadChips deliver affordable, high-quality, genome-wide information across diverse world populations.
|Infinium CoreExome-24 Kit||Infinium Global Screening Array-24 Kit||Infinium OmniExpressExome-8 Kit||Infinium Omni2.5Exome-8 Kit||Infinium Omni5Exome-4 Kit|
|Automation Capability||Automated Array Loader, Liquid Handling Robots||Automated Array Loader, Liquid Handling Robots||Automated Array Loader, Liquid Handling Robots||Automated Array Loader, Liquid Handling Robots||Automated Array Loader, Liquid Handling Robots|
|Description||Includes all of the tag SNPs found on the Infinium Core-24 BeadChip, plus over 240,000 markers from the Infinium Exome-24 BeadChip, with the capacity to add up to 100,000 semi-custom markers for economical large-scale genotyping studies.||An economical next-generation genotyping array that enables population-scale genetics, translational research, variant screening studies, and precision medicine research by combining highly optimized multiethnic genome-wide content, curated clinical research variants, and QC markers.||Offers over 274,000 functional exonic markers while delivering high coverage of putative functional exonic variants selected from over 12,000 individual exome and whole-genome sequences, for studying novel associations with traits and diseases.||Combines >2.5 million tag SNPs from the HapMap and 1000 Genomes projects (>2.5%MAF) with >240,000 markers from the Infinium Exome-24 BeadChip array, to enable genome-wide variation studies while maximizing coverage of functional exonic SNPs.||A high-density array that provides coverage of common, intermediate, and rare SNPs using functional exonic content, for genome-wide genotyping and copy number variation studies.|
|Number of Markers||Fixed markers: 567,218, Custom marker add-on capacity: Up to 100,000 (with + kit versions)||Fixed markers: ~ 654,027
Custom marker add-on capacity: Up to 100,000
|Fixed markers: 958,497, Custom marker add-on capacity: Up to 30,000||Fixed markers: 2,618,000, Custom marker add-on capacity: None||Fixed markers: 4,548,474, Custom marker add-on capacity: None|
|Number of Samples||24 samples per array||24 samples per array||8 samples per array||8 samples per array||4 samples per array|
|Sample Throughput||~2304 samples per week (estimate for 1 iScan System, 1 AutoLoader 2.x, 2 Infinium Automated Pipetting Systems, and a 5-day work week)||~5760 samples/week max per iScan (throughput and scan times may vary based on laboratory and system configurations.)||~960 samples per week (estimate for 2 iScan Systems, 1 AutoLoader 2.x, 2 Infinium Automated Pipetting Systems, and a 5-day work week)||~1728 samples/week per iScan (max throughput and scan time may vary based on lab and system configurations)||~544 samples per week (estimate for 2 iScan Systems, 1 AutoLoader 2.x, 3 Infinium Automated Pipetting Systems, and a 5-day work week)|
The HUNT Biobank and Lifandis AS provide access to biological samples and corresponding clinical data from more than 250,000 individuals in the Norwegian population using Illumina off-the-shelf and custom Infinium HumanExome BeadChips.Learn More
Genesis Healthcare uses the HumanCoreExome+ Array to provide direct-to-consumer genetic testing services that promote health and wellness.Read Interview
Infinium HD Assay Ultra Manual Experienced User Card (11328095) Documentation
Infinium HD Ultra Assay Lab Tracking Form Documentation
Infinium HD Assay Ultra Protocol Guide (11328087) Documentation
Infinium HD Ultra Assay Experienced User Card, Automated Protocol (11328108) Documentation
Infinium Assay Lab Setup and Best Practices Documentation
Infinium Assay Consumables and Equipment List Documentation
Infinium CoreExome-24 Kit Support Documentation
The HumanCoreExome-24 BeadChip Kit has been renamed to Infinium CoreExome-24 Kit. Kits with either name on the label contain the same quality reagents and follow the same workflow.